Tuberculous Spondylitis Caused by Intravesical Bacillus Calmette-Guerin Therapy

Tomokazu Minakata; Yoshio Nakano; Shinobu Tamura; Yamanishi Kazuki; Kana Hayakawa; Takahiro Hayakawa; Takayuki Oota; Tokuzou Fuzimoto; Yukiko Yamano; Takemasa Takii

doi:10.2169/internalmedicine.3288-19

CASE REPORTS (V体育安卓版)

Tuberculous Spondylitis Caused by Intravesical Bacillus Calmette-Guerin Therapy

Tomokazu Minakata, Yoshio Nakano, Shinobu Tamura, Yamanishi Kazuki, Kana Hayakawa, Takahiro Hayakawa, Takayuki Oota, Tokuzou Fuzimoto, Yukiko Yamano, Takemasa Takii

Author information

Keywords: tuberculous spondylitis, Mycobacterium bovis, bacillus Calmette-Guerin

JOURNAL OPEN ACCESS

2020 Volume 59 Issue 5 Pages 733-737

DOI https://doi.org/10.2169/internalmedicine.3288-19

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Abstract

A 74-year-old man underwent intravesical bacillus Calmette-Guerin (BCG) therapy for bladder cancer and later presented with lower left back pain V体育2025版. Magnetic resonance imaging of the spine showed high signal intensity, diagnosed as a cystic lesion in the epidural and bilateral intestinal psoas muscle. A computed tomography-guided needle biopsy and histological examination revealed bacteria from the family Mycobacteriaceae, and Mycobacterium bovis was identified using multiplex polymerase chain reaction. If lower back pain appears in a patient who has undergone BCG therapy, it is necessary to test for tuberculous spondylitis. In addition, QuantiFERON is useful for the differential diagnosis of M. bovis BCG infection. .

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