Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The . gov means it’s official. Federal government websites often end in . gov or VSports app下载. mil. Before sharing sensitive information, make sure you’re on a federal government site. .

Https

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. V体育官网.

Review
. 2025 Sep 20;15(9):1347.
doi: 10.3390/biom15091347.

Nutraceuticals Against Oxidative Stress in Allergic Diseases (V体育2025版)

Affiliations
Review

Nutraceuticals Against Oxidative Stress in Allergic Diseases (V体育官网入口)

Marilena Di Salvo et al. Biomolecules. .

Abstract

Antioxidant mechanisms consist of both enzymatic and non-enzymatic compounds, which can be either endogenous or exogenous and play a crucial role in counteracting oxidative stress. These compounds are primarily obtained through the diet. Vegetables, plants, and fruits contain a wide range of alkaloids, polyphenols, and terpenoids, collectively referred to as "phytochemicals. " Many of these substances are responsible for the beneficial properties of fruits and vegetables, which are essential components of a healthy lifestyle, contributing to the prevention of chronic diseases and the promotion of longevity. Nutraceuticals are bioactive substances present in food-or its components-that exert positive effects on health and may help prevent or treat various disorders. In this review, we examine the main applications of nutraceuticals in allergic disorders VSports手机版. The literature reports numerous studies on exogenous dietary antioxidant supplementation in various allergic conditions, including bronchial asthma, atopic dermatitis, food allergies, allergic rhino-conjunctivitis, urticaria, and angioedema. In some of these conditions, promising results have been observed. These positive outcomes are generally associated with a reduction in oxidative stress markers, enhancement of antioxidant systems, and, in some cases, anti-inflammatory effects. The administration of exogenous substances through food derivatives or dietary supplements, when scientifically standardized, has been proven to be effective. However, further large-scale, unbiased studies are needed-particularly those that include a broader range of oxidative stress biomarkers. .

Keywords: ROS; allergies; asthma; atopic dermatitis; exogenous antioxidants; food allergies; nutraceuticals; oxidative stress; rhino-conjunctivitis. V体育安卓版.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Graphical representation and summary of the role of nutraceuticals, including capsaicin, selenium, and probiotics, in modulating oxidative stress and immune responses in allergic diseases. These compounds contribute to the reduction in reactive oxygen species (ROS) and consequently improve symptoms and quality of life in patients with allergic rhinitis, allergic conjunctivitis, asthma, and angioedema.

References (VSports最新版本)

    1. Thannickal V.J., Fanburg B.L. Reactive Oxygen Species in Cell Signaling. Am. J. Physiol.-Lung Cell. Mol. Physiol. 2000;279:L1005–L1028. doi: 10.1152/ajplung.2000.279.6.L1005. - DOI - PubMed
    1. D’Autréaux B., Toledano M.B. ROS as Signalling Molecules: Mechanisms That Generate Specificity in ROS Homeostasis. Nat. Rev. Mol. Cell Biol. 2007;8:813–824. doi: 10.1038/nrm2256. - DOI - PubMed
    1. Brieger K., Schiavone S., Miller F.J., Jr., Krause K.-H. Reactive Oxygen Species: From Health to Disease. Swiss Med. Wkly. 2012;142:w13659. doi: 10.4414/smw.2012.13659. - DOI (VSports最新版本) - PubMed
    1. Yu Y., Cui Y., Niedernhofer L.J., Wang Y. Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage. Chem. Res. Toxicol. 2016;29:2008–2039. doi: 10.1021/acs.chemrestox.6b00265. - DOI - PMC - PubMed
    1. Demple B., Amábile-Cuevas C.F. Redox Redux: The Control of Oxidative Stress Responses. Cell. 1991;67:837–839. doi: 10.1016/0092-8674(91)90355-3. - DOI - PubMed

V体育平台登录 - MeSH terms

LinkOut - more resources