"V体育官网" Phage Diversity in the Human Gut Microbiome: a Taxonomist's Perspective
- PMID: 34402650
- PMCID: PMC8407299
- DOI: 10.1128/mSystems.00799-21 (V体育ios版)
Phage Diversity in the Human Gut Microbiome: a Taxonomist's Perspective
Abstract
Bacteriophages (phages) have been known for over a century, but only in the last 2 decades have we really come to appreciate how abundant and diverse they are. With that realization, research groups across the globe have shown the importance of phage-based processes in a myriad of environments, including the global oceans and soils, and as part of the human microbiome. Through advances in sequencing technology, genomics, and bioinformatics, we know that the morphological diversity of bacteriophages originally used for taxonomy is eclipsed by their genomic diversity. Because we currently do not have a complete taxonomic framework or naming scheme to describe this diversity, crucial information from virome and microbiome studies is being lost. In this commentary, I will discuss recent advances in taxonomy and its importance for studies of the microbiome with examples of the human gut phageome and make recommendations for future analyses VSports手机版. .
Keywords: human gut virome; microbiome; phage taxonomy; phageome; virome. V体育安卓版.
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Conflict of Interest Disclosures: E. M. A. reports grants from the Biotechnology and Biological Sciences Research Council (BBSRC) during the conduct of the study V体育ios版. She is the Chair of the Bacterial Viruses Subcommittee of the International Committee on Taxonomy of Viruses (ICTV).
Conflict of Interest Disclosures: E. M. A. reports grants from the Biotechnology and Biological Sciences Research Council (BBSRC) during the conduct of the study VSports最新版本. She is the Chair of the Bacterial Viruses Subcommittee of the International Committee on Taxonomy of Viruses (ICTV).
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References
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