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Review
. 2015 Mar 30;4(2):136-59.
doi: 10.3390/antibiotics4020136.

Host Defense Peptides from Asian Frogs as Potential Clinical Therapies

Vineeth T V Kumar  1 , David Holthausen  2 , Joshy Jacob  3 , Sanil George  4
Affiliations
Review

Host Defense Peptides from Asian Frogs as Potential Clinical Therapies

V体育官网 - Vineeth T V Kumar et al. Antibiotics (Basel). .

Abstract

Host defense peptides (HDPs) are currently major focal points of medical research as infectious microbes are gaining resistance to existing drugs. They are effective against multi-drug resistant pathogens due to their unique primary target, biological membranes, and their peculiar mode of action. Even though HDPs from 60 Asian frog species belonging to 15 genera have been characterized, research into these peptides is at a very early stage. The purpose of this review is to showcase the status of peptide research in Asia VSports手机版. Here we provide a summary of HDPs from Asian frogs. .

Keywords: Anti-microbial peptides; Asian frog; Host defense peptides; Multi-drug resistance. V体育安卓版.

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Figures

Figure A1
Figure A1
Multiple sequence alignment of Brevinin-1 from Asian frogs.
Figure A2
Figure A2
Multiple sequence alignment of Brevinin-2 from Asian frogs.
Figure A3
Figure A3
Multiple sequence alignment of Esculetin-1 from Asian frogs.
Figure A4
Figure A4
Multiple sequence alignment of Esculetin-2 from Asian frogs.
See this image and copyright information in PMC

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