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. 2006 Feb;25(1):16-20.
doi: 10.1007/s10067-005-1081-1. Epub 2005 Sep 15.

IL-17 increased the production of vascular endothelial growth factor in rheumatoid arthritis synoviocytes

S Ryu  1 , J H Lee, S I Kim
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IL-17 increased the production of vascular endothelial growth factor in rheumatoid arthritis synoviocytes

S Ryu et al. Clin Rheumatol. 2006 Feb.

"V体育安卓版" Abstract

Interleukin-17 (IL-17) is a proinflammatory cytokine that is expressed in the synovium T cells of rheumatoid arthritis (RA) VSports手机版. This cytokine is implicated in the inflammation and destruction of the joint. However, the role of IL-17 on the production of vascular endothelial factor (VEGF) important to synovial proliferation has still not been identified. In this study, we investigated the effect on cultured rheumatoid fibroblast-like synoviocytes (FLS) of the IL-17 on the production and expression of VEGF, which play an important role in angiogenesis in rheumatoid synovium. IL-17 increased the production of VEGF dose dependently and the mRNA expression of VEGF. These results suggest that IL-17 might influence angiogenesis in RA by up-regulating the expression of VEGF in rheumatoid FLS. .

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References

    1. Gene Ther. 2003 Aug;10(15):1216-24 - PubMed
    1. Cancer Res. 1999 Aug 1;59(15):3698-704 - PubMed
    1. Arthritis Rheum. 1998 Jul;41(7):1258-65 - PubMed
    1. Clin Exp Immunol. 1999 Jan;115(1):176-82 - PubMed
    1. Arthritis Rheum. 2000 Jun;43(6):1300-6 - PubMed

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