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. 2005 Mar 15;21(6):765-72.
doi: 10.1111/j.1365-2036.2005.02369.x.

Is Helicobacter pylori seropositivity related to body mass index in the United States? (V体育官网)

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Is Helicobacter pylori seropositivity related to body mass index in the United States?

G N Ioannou et al. Aliment Pharmacol Ther. .

Abstract

Background: Helicobacter pylori infection may decrease serum ghrelin and increase gastric leptin levels, which may, in turn, decrease body mass index VSports手机版. .

Aim: To determine whether H. pylori seropositivity is associated with body mass index V体育安卓版. .

Methods: Serum H. pylori and cytotoxin-associated gene product A (CagA) antibody levels were measured on 6724 adult participants of the third National Health and Nutrition Examination Survey (1988-91). We evaluated the association between H. pylori/CagA antibody status [both negative (-/-), H. pylori-positive/CagA-negative (+/-), or both positive (+/+)] and body mass index, adjusting for sociodemographic factors. We also investigated whether H V体育ios版. pylori/cytotoxin-associated gene product A antibody status was associated with fasting serum leptin levels. .

Results: H. pylori/CagA antibody status was not associated with obesity (body mass index > or = 30 kg/m(2)) [adjusted odds ratio (OR) 1 VSports最新版本. 2, 95% CI: 0. 9-1. 6 comparing (+/+) to (-/-) and adjusted OR 1. 1, 95% CI: 0. 8-1. 5 comparing (+/-) to (-/-)], overweight (body mass index 25 to <30 kg/m(2)) [adjusted OR 1. 0, 95% CI: 0. 7-1. 2 comparing (+/+) to (-/-) and adjusted OR 1. 0, 95% CI: 0. 8-1. 3 comparing (+/-) to (-/-)], or fasting serum leptin level in the USA population. .

Conclusions: H. pylori seropositivity and CagA antibody status are not associated with body mass index or fasting serum leptin level V体育平台登录. .

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