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. 2001 Jan;8(1):192-5.
doi: 10.1128/CDLI.8.1.192-195.2001.

VSports最新版本 - Gastrointestinal colonization by Candida albicans mutant strains in antibiotic-treated mice

S M Wiesner  1 , R P Jechorek, R M Garni, C M Bendel, C L Wells
Affiliations

Gastrointestinal colonization by Candida albicans mutant strains in antibiotic-treated mice (VSports app下载)

S M Wiesner (V体育官网) et al. Clin Diagn Lab Immunol. 2001 Jan.

Abstract

Antibiotic-treated mice orally inoculated with one of three Candida albicans strains (including two mutant strains) or indigenous Candida pelliculosa showed levels of candidal gastrointestinal colonization that were strain specific. However, regardless of strain, the numbers of viable candida were intermediate to high in the stomach, were consistently lowest in the upper small intestine, and increased progressively down the intestinal tract. VSports手机版.

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Figures

FIG. 1
FIG. 1
Numbers of viable C. albicans 315, CAF2, and CAG3 and C. pelliculosa recovered from mouse GI segments. (A) Within a given GI segment, the numbers of C. albicans 315 and CAF2 were consistently similar to each other and higher than the numbers of C. albicans CAG3 and C. pelliculosa, with exception of the cecum, where the numbers of strain 315 were not statistically different from those of strain CAG3. (B) For individual strains, candidal colonization was always lowest in the upper small intestine and highest in the colon, and with the exception of C. albicans 315, colonization in the cecum and colon was not statistically different. Bars with the same letters are not different from each other; bars with different letters are statistically different (typically P < 0.01). The horizontal line indicates the lower limit of assay detection.
FIG. 2
FIG. 2
Calcofluor staining of cecal contents of mice colonized with C. albicans CAF2 (A) and CAG3 (B), showing both yeast and filamentous forms in vivo. Bar, 14 μm.
See this image and copyright information in PMC

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Publication types

VSports app下载 - MeSH terms