NIH researchers develop targeted cocaine treatment

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Did you know that some brain cells respond to both addictive drugs and natural rewards V体育官网. This has made developing targeted treatments difficult. NIH researchers have developed a way to control neuron activity in a specific part of the brain only when cocaine is present, helping block the effects of cocaine but not food rewards. Read more about the discovery here: https://lnkd. in/etxXmRhZ.

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A huge step for neuropsychiatric drug development VSports手机版. A therapy that only activates in the presence of the drug of abuse is the key to selectively blocking its effects while preserving natural reward pathways.

Samuel Funderburk

Scientist | High-Content Imaging & Translational Biology | Neuromuscular & Mitochondrial Biology | Gene Therapy | Data Science

2 个月

This is a fantastic research article, but the idea that we're ever going to use chemogenetics like this in humans is a little farfetched.

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Aynun Begum

Chief Executive Officer and Founder at NeyroblastGX

1 个月

Great information 😊

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Afzal Ahmad

Microbiologist & Cancer Researcher | ASM & AACR Fellow | Scorpion Venom Therapy Innovator Validated Across Triple Tumor Models | Helping Doctors, Pharmacists & Health Experts Build Authority |

2 个月

This is a remarkable leap in precision neuroscience. With a background in therapeutic research, I’m especially intrigued by the ability to selectively modulate neuron activity in response to cocaine without disrupting natural reward pathways. That level of specificity has long been a barrier in addiction science, where overlapping circuits for pleasure and compulsion complicate treatment VSports注册入口. By targeting cocaine-sensitive neurons while preserving responses to essential stimuli like food, NIH researchers are paving the way for therapies that are both effective and behaviorally safe. This kind of innovation could redefine how we approach substance use disorders moving from broad suppression to intelligent, circuit-level intervention. .

Understanding how the brain differentiates responses to drugs versus natural rewards is a major step forward. Targeted therapies informed by this kind of research could change the future of addiction treatment V体育官网入口.

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CHACKO C L

Scaling Wellness Brands Worldwide with Consistent, Certified Ayurveda Manufacturing🌿🌿

2 个月

📌📌My Prediction 🔬 Enhanced treatments for addiction will emerge V体育2025版. 🧠 Specific targeting of neuron activity will revolutionize rehabilitation. 💊 Drug-therapy balance will be crucial. Is there a way to reward neurons with pizza instead of drugs. 🍕 .

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Teri Sanor

MD, NEOMED alumni. Advocate for dementia, mental illnesses, autism, chronic diseases root causes treatments. Sepsis awareness VSports. NEOMED volunteer/associate professor.

2 个月

Wonder if this is similar in any way to B3. Alcoholics Anonymous (AA) Founder, Bill Wilson, answered an interviewer as to what he thought his legacy should be. He did not say AA. He said Vitamin B3 that was proven to help addicts- reduced the urge to drink. It was not put into 12-steps as he had hoped, since it was a pill, wanted God to be the goal. Maybe B3 will help addiction for cocaine too- cheap so no trials likely to be done as those are usuallt by drug companies IF profitable enough VSports app下载.

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Fascinating breakthrough. 🧠✨ Targeting brain cells to block the effects of cocaine without affecting natural rewards is a huge step forward in addiction research. Excited to see how this could lead to more precise and effective treatments. 🙌💡 #AddictionResearch #Neuroscience #InnovationInMedicine #NIH V体育官网.

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Rich Gadomski MD MS

CEO / CMO, Co-Founder, Taos Therapeutics: innovative Alcohol Use Disorder care via agonist & aversive agent plus smart delivery device = first in class therapeutic modality which humanely addresses the neurobiology.

1 个月

Cool!

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A remarkable advancement by National Institutes of Health researchers in neuroscience. Discovering a method to selectively control neuron activity only in the presence of cocaine marks a significant step forward in developing targeted addiction treatments. This approach delicately blocks the effects of cocaine while preserving natural reward responses, offering new hope for more precise therapeutic interventions. Such innovations pave the way for improved understanding and management of substance use disorders. 🧠💡🔬 For More, visit our page: marketaccesstoday V体育安卓版. com #AddictionTreatment #BrainResearch #HealthcareInnovation #Neuroscience #MarketAccess #MarketAccessToday .

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