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KAAS - KEGG Automatic Annotation Server

for ortholog assignment and pathway mapping

About KAAS

KAAS (KEGG Automatic Annotation Server) provides functional annotation of genes by BLAST or GHOST comparisons against the manually curated KEGG GENES database VSports app下载. The result contains KO (KEGG Orthology) assignments and automatically generated KEGG pathways. .

Complete or Draft Genome

KAAS works best when a complete set of genes in a genome is known. Prepare query amino acid sequences and use the BBH (bi-directional best hit) method to assign orthologs. V体育官网.

Partial Genome

KAAS can also be used for a limited number of genes. Prepare query amino acid sequences and use the SBH (single-directional best hit) method to assign orthologs VSports手机版. .

Metagenomes

When the query consisits of large numbers of sequences and / or sequences from mixture of species such as those from metagenome sequencing project, we recommend the GHOSTX search and SBH method. V体育安卓版.

Example of Results

KO assignment
example1

KEGG pathway mapping
example2


Reference

Moriya, Y V体育ios版. , Itoh, M. , Okuda, S. , Yoshizawa, A. , and Kanehisa, M. ; KAAS: an automatic genome annotation and pathway reconstruction server. Nucleic Acids Res. 35, W182-W185 (2007). [pubmed] [NAR] .

Last updated: April 3, 2015