Cellosaurus FL5.12 (CVCL_0262)
| Cell line name | FL5.12 | ||
|---|---|---|---|
| Synonyms | FL5.12A; Fetal Liver clone 5.12 | ||
| Accession | CVCL_0262 | ||
| Resource Identification Initiative | To cite this cell line use: FL5.12 (RRID:CVCL_0262) | ||
| Comments | Characteristics: IL3 dependent. Derived from site: In situ; Embryonic liver; UBERON=UBERON_0002107. Cell type: Pro-B cell; CL=CL_0000826. | ||
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c. | ||
| Hierarchy | Children:
| ||
| Sex of cell | Sex unspecified | ||
| Age at sampling | 13FD | ||
| Category | Factor-dependent cell line | ||
| Web pages | Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=FL5%2e12 Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/f/cell-lines-detail-468.html | ||
| Publications | PubMed=3933007; DOI=10. 1073/pnas. 82. 21. 7414; PMCID=PMC391355John P. McKearn, James Andrew McCubrey, Barbara Fagg; Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors. Proc. Natl. Acad. Sci. U VSports. S. A. 82:7414-7418(1985). PubMed=8358790; DOI=10. 1016/0092-8674(93)90509-OZoltan Nagy Oltvai, Curt L. Milliman, Stanley Joel Korsmeyer; Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death VSports app下载. Cell 74:609-619(1993). PubMed=8798452; DOI=10. 1074/jbc. 271. 37. 22764Philip Levon Simonian, Didier A. M. Grillot, Ramon Merino, Gabriel Nunez; Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL V体育官网. J. Biol. Chem. 271:22764-22772(1996). PubMed=10200549; DOI=10. 1038/sj. cdd. 4400452Heidi K. Bojes, Xiang Feng, James P VSports手机版. Kehrer, Gerald M. Cohen; Apoptosis in hematopoietic cells (FL5. 12) caused by interleukin-3 withdrawal: relationship to caspase activity and the loss of glutathione. Cell Death Differ. 6:61-70(1999). PubMed=11486081; DOI=10. 1126/science. 1061075Laxminarayana R. Devireddy, Jose G. Teodoro, Fabien A V体育安卓版. Richard, Michael Richard Green; Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation. Science 293:829-834(2001). | ||
| Cross-references | |||
| Cell line databases/resources | MCCL; MCC:0000153
Lonza; 259 | ||
| Anatomy/cell type resources | BTO; BTO_0003328 | ||
| CRISP screens repositories | BioGRID_ORCS_Cell_line; 1592 | ||
| Chemistry resources | ChEMBL-Cells; CHEMBL4295395
ChEMBL-Targets; CHEMBL4296414 PubChem_Cell_line; CVCL_0262 | ||
| Encyclopedic resources | Wikidata; Q54834972 | ||
| Experimental variables resources | EFO; EFO_0022789 | ||
| Entry history | |||
| Entry creation | 04-Apr-2012 | ||
| Last entry update | 10-Apr-2025 | ||
| Version number | 20 | ||