Zihuai recipe alleviates cyclophosphamide-induced diminished ovarian reserve via suppressing PI3K/AKT-mediated apoptosis

Rehmannioside D mitigates disease progression in rats with experimental-induced diminished ovarian reserve via Forkhead Box O1/KLOTHO axis

Liang1, Wang2, Chen3 et al. 2023Korean J Physiol Pharmacol5000Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…FOXOs are deemed as downstream targets of PI3K/AKT, and FOXO phosphorylation is induced by phosphorylated AKT, which leads to suppression of FOXO transcription [ 40 ]. There has been convincing evidence manifesting that Zihuai recipe alleviated CTX-DOR by suppressing PI3K/AKT pathway-mediated ovarian cell apoptosis [ 7 ]. Likewise, Dingkun Pill enhanced ovarian reserve by suppressing the PI3K/AKT/mTOR signaling pathway in DOR rats [ 41 ] VSports. …”Section: Discussionmentioningconfidence: 99%“…Granulosa cell apoptosis has been shown to be disordered in DOR, which has significant consequences on the generation of empty follicles, oocyte retrieval, and the quality of oocytes and embryos [ 6 ]. Currently, hormone replacement therapy (HRT) is a commonly used treatment for pathologic DOR, but the long-term outcome of HRT is poor [ 7 ]. Although there have been a number of studies on DOR, the optimal treatment for pathologic DOR is still undetermined. …”Section: Introductionmentioningconfidence: 99%

Rehmannioside D mitigates disease progression in rats with experimental-induced diminished ovarian reserve via Forkhead Box O1/KLOTHO axis

Liang1, Wang2, Chen3 et al. 2023Korean J Physiol Pharmacol5000Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…After oral administration, it is absorbed the gastrointestinal tract and degraded in the liver. [13] The Foley balloon has the function of filling the patient's uterine cavity, covering the wound and forming a biological barrier, avoiding uterine adhesions during the patient's postoperative recovery process, and is conducive to the repair of endometrial hyperplasia. [14] According to the results of this study, after receiving different treatment regimens for 2 months, compared with the control group, the observation group achieved higher curative effect, shorter abdominal pain duration, vaginal bleeding duration and refluid time, and lower vaginal bleeding. …”Section: Discussionmentioningconfidence: 99%“…After oral administration, it is absorbed through the gastrointestinal tract and degraded in the liver. [13] The Foley balloon has the function of filling the patient’s uterine cavity, covering the wound and forming a biological barrier, avoiding uterine adhesions during the patient’s postoperative recovery process, and is conducive to the repair of endometrial hyperplasia. [14]…”Section: Discussionmentioningconfidence: 99%

To study the current status of uterine adhesions after fetal residue and the preventive effect of using estrogen and progesterone sequential therapy combined with Foley balloon

Liu1, Wang2, Li3 et al. 2022Medicine2010Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Statistical comparisons were analyzed by one-way analysis of variance (ANOVA). A value of p < 0. 05 suggests a difference, and p < 0. 01 represents a significant difference ( Chen et al, 2019 ; Liu et al, 2021 ). …”Section: Methodsmentioningconfidence: 99%

Pharmacological effects of Bufei Jianpi granule on chronic obstructive pulmonary disease and its metabolism in rats

Yang1, Wang2, Cui3 et al. 2022Front. Pharmacol. 7080Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 3 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.