"V体育官网" Extracellular DNA Correlates with Intestinal Inflammation in Chemically Induced Colitis in Mice

Neutrophil Extracellular Traps in Colorectal Cancer Progression and Metastasis

Khan1, Chowdhury2, Billah3 et al. 2021IJMS820950Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…NETs have been implicated in many gastrointestinal diseases including inflammatory bowel diseases (IBDs) [ 39 , 40 , 41 ], liver disease [ 35 ], and acute pancreatitis [ 42 , 43 , 44 ]. A chronic abiding repetitive event of inflammation in intestinal epithelium is portrayed as IBD [ 39 ]. …”Section: Nets In Gastrointestinal Inflammationmentioningconfidence: 99%“…NETs have been implicated in many gastrointestinal diseases including inflammatory bowel diseases (IBDs) [ 39 , 40 , 41 ], liver disease [ 35 ], and acute pancreatitis [ 42 , 43 , 44 ]. A chronic abiding repetitive event of inflammation in intestinal epithelium is portrayed as IBD [ 39 ]. Aberrant NET accumulation and the deterioration of inflamed intestinal barrier integrity can be correlated with IBD [ 39 ], as in ulcerative colitis (UC) [ 40 ]. …”Section: Nets In Gastrointestinal Inflammationmentioningconfidence: 99%“…A chronic abiding repetitive event of inflammation in intestinal epithelium is portrayed as IBD [ 39 ]. Aberrant NET accumulation and the deterioration of inflamed intestinal barrier integrity can be correlated with IBD [ 39 ], as in ulcerative colitis (UC) [ 40 ]. Neutrophils and NET-associated molecules are found in abundance in both colonic biopsies of UC [ 45 , 46 ] and Crohn’s disease (CD) [ 41 ], which indicate intestinal inflammatory aggravation, epithelial exasperation, and elevated thrombotic impulse [ 47 ]. …”Section: Nets In Gastrointestinal Inflammationmentioningconfidence: 99%“…Administration of dextran sulfate sodium (DSS) [ 36 , 46 ] or 2,4,6-trinitrobenzene sulfonic acid (TNBS) [ 40 ] can induce murine UC, principally by disrupting intestinal epithelial barrier and eliciting a number of chronic immunologic responses. In the mouse model, increased DSS consumption can elevate the plasma level of extracellular DNA (ecDNA) in the form of NETs, which in turn induces UC [ 39 ]. The elevated response is correlated with the amplitude of disease severity and relative proportion of cells undergoing NETosis. …”Section: Nets In Gastrointestinal Inflammationmentioningconfidence: 99%“…The elevated response is correlated with the amplitude of disease severity and relative proportion of cells undergoing NETosis. However, the initial administration of protein-arginine deaminase type 4 (PAD4) inhibitors, Cl-amidine and streptonigrin can curb the formation of NETs, and in turn decrease the plasma ecDNA level in UC [ 39 ]. Some other studies have reported that the systemic administration of DNase can lead to amelioration of DSS-induced colitis by dissolving NETs [ 39 , 47 ]. …”Section: Nets In Gastrointestinal Inflammationmentioningconfidence: 99%See 3 more Smart Citations

"V体育2025版" Neutrophil Extracellular Traps in Colorectal Cancer Progression and Metastasis

Khan1, Chowdhury2, Billah3 et al. 2021IJMS820950Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract

Neutrophil extracellular trap induction through peptidylarginine deiminase 4 activity is involved in 2,4,6-trinitrobenzenesulfonic acid-induced colitis

Yasuda1, Uno2, Tanaka3 et al. 2023Naunyn-Schmiedeberg's Arch Pharmacol3030Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD) VSports app下载. Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

Extracellular DNA and Deoxyribonuclease Activity as Potential Biomarkers of Inflammation in Multiple Sclerosis (V体育ios版)

Marček1, Kadlic2, Adamová3 et al. 2025Mol Neurobiol0000Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 3 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.