Tryparedoxin peroxidase-deficiency commits trypanosomes to ferroptosis-type cell death (V体育安卓版)

Liver stage malaria infection is controlled by host regulators of lipid peroxidation

Kain1, Glennon2, Vijayan3 et al. 2019Cell Death Differ771680Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…The effect of knockdown of host factors, not present in the parasite, on LS infection and parasite-localized lipid peroxidation suggests that ROS production and lipid peroxidation are, at least partially, driven by host cell signaling. It is also possible that the Plasmodium parasite itself is susceptible to ferroptosis-like cell death, as has been described in trypanosomes [37]. Whether the lipids that undergo peroxidation are of host and/or parasite origin, and how this leads to parasite clearance, are important topics for future investigation. …”Section: Discussionmentioningconfidence: 97%

Liver stage malaria infection is controlled by host regulators of lipid peroxidation

Kain1, Glennon2, Vijayan3 et al. 2019Cell Death Differ771680Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD) VSports app下载. Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Fer-1 is the first ferroptosis inhibitor, and is widely used in vitro and in vivo [44][45][46][47]. The function of Fer-1 against ferroptosis mainly depends on the inhibition of lipid peroxidation. …”Section: Discussionmentioningconfidence: 99%

Ferrostatin-1 alleviates lipopolysaccharide-induced acute lung injury via inhibiting ferroptosis

Liu1, Feng2, Li3 et al. 2020Cell Mol Biol Lett560163280Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…3c). Altogether, these results indicate that cyanobacterial cells exposed to a 50°C-undergo an oxidative, iron-dependent form of cell death remarkably similar to ferroptosis in eukaryotic cells (Dixon et al, 2012;Distéfano et al, 2017;Bogacz and Krauth-Siegel, 2018;Dangol et al, 2018). …”mentioningconfidence: 68%“…In eukaryotic organisms, cytoplasmic ROS and lipid ROS accumulation play a central and essential role in the ferroptotic pathway. The oxidative burst observed in eukaryotic cells undergoing ferroptosis is dependent on iron as it is prevented by iron chelators (Bogacz and Krauth-Siegel, 2018;Distéfano et al, 2017;Dixon et al, 2012). …”Section: ºC Heat Shock-induced Cell Death Involves Rapid Accumulatimentioningconfidence: 99%“…Different types of RCD have been described in eukaryotes (Melino et al, 2005;Minina et al, 2013). Among them, ferroptosis was recently reported as an oxidative, iron-dependent form of RCD associated with lipid peroxidation and ROS accumulation present in animals, plants and protozoan parasites (Bogacz and Krauth-Siegel, 2018;Conrad et al, 2018;Dangol et al, 2018;Distéfano et al, 2017;Dixon et al, 2012;Stockwell et al, 2017). …”Section: Introductionmentioningconfidence: 99%See 1 more Smart Citation

Heat stress induces ferroptosis in a photosynthetic prokaryote

Aguilera1, Berdun2, Bartoli3 et al. 2019Preprint4060Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 3 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.