Gut Microbiota as a Modulator of Paneth Cells During Parenteral Nutrition in Mice

"V体育平台登录" Enteral Nutrition in Pediatric Patients Undergoing Hematopoietic SCT Promotes the Recovery of Gut Microbiome Homeostasis

D’Amico1, Biagi2, Rampelli3 et al. 2019Nutrients805740Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…On the other hand, PN patients were found have blood culture positivity to several microorganisms (e. g. , Staphylococcus, Enterococcus and Streptococcus genera), mainly from day 5 to 30 post-HSCT, leading to systemic infections and clinical complications. Our results regarding the clinical outcomes of EN patients were generally in line with most of the previous studies in literature conducted on adult cohorts post-HSCT [18][19][20][21][22][23]. However, we cannot fail to mention that other studies provide conflicting results for what concern the clinical outcomes of EN assumption in HSCT adult patients [52,53]. …”Section: Discussionsupportingconfidence: 89%“…Although post-HSCT enteral feeding is being increasingly recommended [37][38][39], intravenous nutrient intake (PN) is still the first-line nutritional approach for the patients who received HSCT due to its compliance, but it has been associated with several clinical and microbiological adverse effects, including infections and GM dysbiosis [18][19][20][21][22][23][24]. So far, the central role of the GM composition and biodiversity in patients undergoing HSCT has been largely evaluated in several publications, highlighting the disruption of the gut microbial mutualistic asset after the transplant (i. e. , until 30 days post-HSCT) compared to the baseline, due to all HSCT conventional treatments that can alter the GM recovery possibilities post-HSCT [4,5,7]. …”Section: Discussionmentioningconfidence: 99%“…EN, also called "tube-feeding", is the method by which food is directly delivered inside the patient's gastrointestinal tract, while PN is an effective strategy of delivering nutrients directly into the bloodstream. Nowadays, it is well known that total PN, the first-line approach for HSCT patients, is associated with different clinical adverse effects such as infections [18][19][20] and metabolic disorders [21], as well as with gut mucosal atrophy [22], cell dysfunction [23], and alterations in GM composition [24]. Conversely, EN has been indicated as a possible solution to overcome all these adverse effects. …”Section: Introductionmentioningconfidence: 99%See 1 more Smart Citation

Enteral Nutrition in Pediatric Patients Undergoing Hematopoietic SCT Promotes the Recovery of Gut Microbiome Homeostasis

D’Amico1, Biagi2, Rampelli3 et al. 2019Nutrients805740Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…In T2DM, the altered gut microbiota potentially affect the fecal metabolome, the immune status and the intestinal redox status and inflammation (Lopez- de-Andres et al, 2018;Piccolo et al, 2018;Wang et al, 2018;Tian et al, 2019). T2DM was reportedly affected by the decrease of butyrate-producing species in rats (Li et al, 2019;Zhou et al, 2019). …”Section: Figure 4 | (A)mentioningconfidence: 99%

Single-Anastomosis Duodenal Jejunal Bypass Improve Glucose Metabolism by Regulating Gut Microbiota and Short-Chain Fatty Acids in Goto-Kakisaki Rats

Yu1, Wu2, Song3 et al. 2020Front. Microbiol VSports app下载. 243220Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…In Crohn's disease patients the combination of tobacco smoking and the ATG16L1 polymorphism combine to trigger Paneth cell defects and apoptosis (97). Acute antibiotic treatment is known to decrease the protein level of lysozyme and of RegIIIγ as well as the mRNA level of αdefensin 5 (98). However, the long-term effects of "earlier in life" antibiotic treatment are unknown and therefore the analogy to patients with antibiotics in childhood and later Crohn's disease is speculative. …”Section: The Paneth Cell and Environmental Riskmentioningconfidence: 99%

An Update Review on the Paneth Cell as Key to Ileal Crohn's Disease

Wehkamp1, Stange2 2020Front. Immunol. 940870Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 4 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.