Gut microbiota in the pathogenesis of inflammatory bowel disease (VSports)

The S100B story: from biomarker to active factor in neural injury

Michetti1, D’Ambrosi2, Toesca3 et al. 2018Journal of Neurochemistry35893241Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…In pathological conditions, inflammation can convert EGCs to a 'reactive EGC phenotype', resembling the behavior of astrocytes in the central nervous system (Sharkey 2015;Ochoa-Cortes et al 2016). Ulcerative colitis and Crohn's disease are the two major clinically defined forms of inflammatory bowel disease (for review, Nishida et al 2018). Although dysfunction of the mucosal immune system undoubtedly plays a role in the pathogenesis of inflammatory bowel disease (Kim and Cheon 2017), a role for the enteric nervous system (Goyal and Hirano 1996), located within the wall of the gastrointestinal tract, has been recognized in intestinal inflammation, also involving interactions with the intestinal microbiota (Margolis and Gershon 2016). …”Section: Congenital/perinatal Disordersmentioningconfidence: 99%

The S100B story: from biomarker to active factor in neural injury (VSports app下载)

Michetti1, D’Ambrosi2, Toesca3 et al. 2018Journal of Neurochemistry35893241Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…The human body is inhabited by a huge number of microbes, most of which are bacteria and archaea, fungi and microeukaryotes . In fact, the gut is the home to more than 100 trillion microorganisms, which constitute approximately 10 times the number of cells and 100 times the number of genes that are encoded in the human body . Intestinal microbiota mainly colonize in the gastrointestinal (GI) tract, especially in the colon, as the latter mainly provides an aerobic and nutritional environment that makes it the preferred site for intestinal microbes . …”Section: The Integrity Of Intestinal Mucosal Barrier Depends On Gut Mmentioningconfidence: 99%“…Furthermore, the composition of gut microbiota can influence the host response to pathogens as well as its predisposition to disease . However, the partnership between the gut and its microbiota is not always in balance, and an ever‐growing number of disorders are linked to the dysbiosis of the resident microbiota …”Section: The Integrity Of Intestinal Mucosal Barrier Depends On Gut Mmentioningconfidence: 99%

Gut microbiota in ulcerative colitis: insights on pathogenesis and treatment

Guo1, Liu2, Hao3 2020J of Digest Diseases26531870Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Alteration in the gut microbiome may affect intestinal integrity and increase gut permeability leading to local and systemic immune response . Intestinal barrier disruption, along with genetic background and environmental factors, has been recently considered as a pivotal element in the pathogenesis of chronic inflammatory diseases, including inflammatory bowel disease and celiac disease . Recent experimental and clinical studies revealed disturbance in the balance of beneficial and pathogenic bacteria in the gut of patients with psoriasis and psoriatic arthritis . …”Section: Introductionmentioningconfidence: 99%“…3 Intestinal barrier disruption, along with genetic background and environmental factors, has been recently considered as a pivotal element in the pathogenesis of chronic inflammatory diseases, including inflammatory bowel disease and celiac disease. 4,5 Recent experimental and clinical studies revealed disturbance in the balance of beneficial and pathogenic bacteria in the gut of patients with psoriasis and psoriatic arthritis. [6][7][8] However, it remains unclear whether alteration in the gut microbiome and inflammatory processes in psoriasis influence the intestinal barrier. …”Section: Introductionmentioningconfidence: 99%

Intestinal barrier integrity in patients with plaque psoriasis

Sikora1, Chrabąszcz2, Maciejewski3 et al. 2018The Journal of Dermatology587370Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD) VSports app下载. Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 3 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.