Sex and strain-based inflammatory response to repeated tobacco smoke exposure in spontaneously hypertensive and Wistar Kyoto rats

Beta-2 Adrenergic and Glucocorticoid Receptor Agonists Modulate Ozone-Induced Pulmonary Protein Leakage and Inflammation in Healthy and Adrenalectomized Rats

Henriquez1, Snow2, Schladweiler3 et al. 2018Toxicological Sciences341461Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…The dynamic nature of ozone-induced changes was not examined to determine how the recovery or progression of injury might occur after ozone exposure, especially in the case of AD. Furthermore, only male WKY rats were used since males of a strain derived from WKY, the spontaneously hypertensive rats, have shown greater sensitivity to tobacco smoke-induced lung injury and inflammation than females (Shen et al, 2016). However, ozoneinduced effects have not been examined in female WKY rats. …”Section: Discussionmentioningconfidence: 99%

Beta-2 Adrenergic and Glucocorticoid Receptor Agonists Modulate Ozone-Induced Pulmonary Protein Leakage and Inflammation in Healthy and Adrenalectomized Rats

Henriquez1, Snow2, Schladweiler3 et al. 2018Toxicological Sciences341461Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…The left lung lobe was inflation-fixed at 30-cm water pressure with 4% paraformaldehyde for 1 hour and embedded in paraffin wax for subsequent histological analysis. 18,23…”Section: Methodsmentioningconfidence: 99%“…28 Resulting images were projected onto a monitor using an Axiocam 105 color camera (Zeiss, Jena, Germany) and overlaid with a test grid generated by Stereology Toolbox software (Morphometrix, Davis, California) to assess MLI by counting the number of points intercepting alveolar tissue. 18,29 The airspace size was expressed as the average length of the line between intercepts in µm and was compared between TS and FA groups. …”Section: Methodsmentioningconfidence: 99%“…12,13 In the present study, the spontaneously hypertensive (SH) rat model was used to examine the effects of chronic TS exposure. Based on previous work, [14][15][16][17] and in contrast to other rodent models, 18 the SH rat appears to be an optimal model for TS-induced lung inflammation with significant cellular, inflammatory, and structural changes in the lung consistent with human smokers VSports app下载. A striking finding in SH rats is the rapidity with which these pathologic changes develop following limited periods of smoking at fairly low concentrations of TS. …”Section: Introductionmentioningconfidence: 99%See 1 more Smart Citation

VSports注册入口 - Long-Term Sequelae of Smoking and Cessation in Spontaneously Hypertensive Rats

Wu1, Yau2, Fulgar3 et al. 2019Toxicol PatholSelf Cite7020Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…48 These rats are now used worldwide in understanding of the key susceptibility attributes associated with hypertensive disorder in exacerbating pulmonary and cardiovascular effects of air pollutants. 49 –54…”Section: Use Of Animal Models Of Human Cardiovascular Diseases In Airmentioningconfidence: 99%

"V体育官网入口" Susceptibility Variations in Air Pollution Health Effects: Incorporating Neuroendocrine Activation

Kodavanti1 2019Toxicol PatholSelf Cite280110Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 3 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.