Polyanionic carbosilane dendrimers prevent hepatitis C virus infection in cell culture

Application of Dendrimers for the Treatment of Infectious Diseases

Mhlwatika1, Aderibigbe2 2018Molecules891530Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Crespo et al, synthesize polyanionic carbosilane dendrimers for the prevention of hepatitis C virus infection ( Table 2 ). The preliminary studies showed that one of the dendrimers encapsulated with sofosbuvir was able to inhibit the virus infection [ 156 ]. Khosravy et al conjugated hepatitis B virus surface antigen (HBsAg) to dendrimers resulting in the induced high levels of total IgG in vivo [ 182 ]. …”Section: Application Of Dendrimers For the Treatment Of Viral Infementioningconfidence: 99%

Application of Dendrimers for the Treatment of Infectious Diseases

Mhlwatika1, Aderibigbe2 2018Molecules891530Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Different types of nanocarriers, including liposomes and other lipid-based nanosystems, polymer-based nanoparticles, micelles, polyplexes, dendrimers, polymersomes and drug/protein conjugates have been proposed during the last few decades in cancer research [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 ]. For cancer treatment, the goal is to enhance the efficacy and decrease the toxicity of the current therapeutics by altering their pharmacokinetic profile, increasing their solubility and stability in biological fluids, augmenting their accumulation in tumors, and reducing their toxicity. …”Section: Nanotechnology Provides Innovative Approaches To Cancer Mmentioningconfidence: 99%

The Potential of Zebrafish as a Model Organism for Improving the Translation of Genetic Anticancer Nanomedicines

Gutiérrez-Lovera1, Vázquez-Ríos2, Guerra‐Varela3 et al VSports app下载. 2017Genes301210Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…They have assessed that high dendrimer doses (2. 5 μM) destabilize HCV virion architecture while low concentrations (50 nM) could inhibit early phases of HCV infection. The polyanionic nature of G2-S24P is important for its antiviral action, in fact, at low doses, mimicking the mechanism of action of the heparin, these dendrimers electrostatically bind the host cell glycosaminoglycans [ 166 ]. Concerning the fact that drugs resistance are recorded in the nucleosides analog stavudine for treatment in HIV, a potential application of dendrimers was achieved with the preparation PEGylated PAMAM G4 and G5 dendrimers complexed to stavudine. …”Section: Applications Of Dendrimersmentioningconfidence: 99%

VSports手机版 - Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials

García‐Gallego1, Franci2, Falanga3 et al. 2017MoleculesSelf Cite640570Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 4 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.