Characterizing human lung tissue microbiota and its relationship to epidemiological and clinical features (V体育ios版)

"V体育平台登录" The respiratory microbiome in bronchial mucosa and secretions from severe IgE-mediated asthma patients

Millares1, Bermudo2, Pérez‐Brocal3 et al. 2017BMC Microbiol262220Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…To our knowledge, the presence of this genus in the bronchial mucosa of patients with chronic respiratory diseases such as asthma has not been previously reported, and future studies focusing on its role in patients following regular treatment with corticosteroids will be needed. Legionella species have been identified in non-malignant lung tissue obtained from lung cancer patients who underwent surgical resection [54], a finding in agreement with the hypothesis that Legionella may persist in human cells, against the common criteria that these microorganisms may be only found in patients with acute respiratory symptoms. Legionella is able to replicate intracellularlly in macrophages that have phagocytized aerosolized bacteria, and several studies have shown that Legionella pneumophila creates endoplasmic reticulum (ER)-like vacuoles that support intracellular replication. …”Section: Discussionsupportingconfidence: 70%

The respiratory microbiome in bronchial mucosa and secretions from severe IgE-mediated asthma patients

Millares1, Bermudo2, Pérez‐Brocal3 et al. 2017BMC Microbiol262220Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…A recent study, in which surgical lung tissue samples were used, concluded that the microbiota of the lung is unique, with proteobacteria as the dominant genera (Yu et al, 2016). …”Section: Lung Cancermentioningconfidence: 99%“…Colorectal cancer (CRC) is one of the primary causes of death worldwide (Zackular et al, 2013). Ferlay et al (2013) has determined that CRC is the third leading cancer, with 1. 4 million new cases diagnosed in 2012. …”Section: Colorectal Cancermentioningconfidence: 99%“…The KRAS (v-Ki-ras2 Kirsten rat sarcoma viral oncogene homologue) gene codes for a GTPase that controls cellular proliferation and is mutated in 50-60 % of CRC cases (Kerr, 2003;Louis et al, 2014). While genetic predisposition has been related to risk, clinical and experimental evidence also supports a relationship with diet and lifestyle (Greer & O'Keefe, 2011;Louis et al, 2014;Zackular et al, 2013), including important risk factors such as the consumption of red and processed meats and alcohol, and chronic inflammation of the gastrointestinal tract (colitis-associated cancer in individuals with IBD) (Louis et al, 2014). A large body of evidence supports a relationship between infective agents and human cancers, and suggests that certain mucosa-associated bacterial species play an important role in the pathogenesis of CRC (Marchesi et al, 2011). …”Section: Colorectal Cancermentioningconfidence: 99%“…Evidence regarding the contribution of the intestinal microbiota to the aetiology of pathological conditions, such as IBD and CRC, is increasing, with microorganisms belonging to the microbial community no longer simply being considered 'spectators' (Arthur & Jobin, 2011), but as metabolically active residents that strongly influence processes that maintain homeostasis or promote carcinogenesis (Zackular et al, 2013). …”Section: Colorectal Cancermentioningconfidence: 99%See 2 more Smart Citations

"VSports" Microbiota dysbiosis: a new piece in the understanding of the carcinogenesis puzzle

García-Castillo1, Sanhueza2, McNerney3 et al. 2016Journal of Medical Microbiology1131830Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract

Linking microbiota and respiratory disease

Hauptmann1, Schaible2 2016FEBS Letters720560Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 4 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility VSports app下载. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.