"VSports" Classical dendritic cells are required for dietary antigen–mediated induction of peripheral Treg cells and tolerance

"VSports app下载" Dendritic Cells As Inducers of Peripheral Tolerance

Iberg1, Jones2, Hawiger3 2017Trends in Immunology15941900Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…In addition to targeting of DCs with recombinant chimeric antibodies antigens may also be delivered to DCs using single-chain fragment variable (scFv) containing antigenic peptides as well as antibodies which are produced via chemical conjugation of the antigen protein to the heavy chain of the original monoclonal antibodies such as anti-DNGR-1/CLEC9A or anti-DEC205 [56, 106, 116]. Further, other methods of non-targeted antigen delivery have been used, such as oral administration of proteins that may be processed and presented by cDCs in the intestines [27]. Additionally, tolerogenic microparticles are predominantly taken up by monocytes and macrophages and possibly such antigens might then be also further acquired by DCs [109]. …”Section: Establishing the Roles Of Dcs As Key Inducers Of Peripheral mentioningconfidence: 99%

Dendritic Cells As Inducers of Peripheral Tolerance (V体育平台登录)

Iberg1, Jones2, Hawiger3 2017Trends in Immunology15941900Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…[131][132][133][134][135] Thymic DCs induce Treg-cell development via production of IL-2, 136 and that CD11b( − ) cDCs from the gut-draining lymph nodes were critical for induction of peripheral Treg cells and oral tolerance. 137 The presence of exogenous immunosuppressive mediators, genetic manipulation, specific pathogenic stimuli also induce regulatory property of DCs through various mechanisms. 138 The cross-presentation of exogenous antigens via MHC class I molecules to initiate CTL responses is essential for immunological defense against viruses, intracellular bacteria and tumors. …”Section: Dendritic Cellsmentioningconfidence: 99%

Cellular and molecular regulation of innate inflammatory responses

Liu1, Cao2 2016Cell Mol Immunol16131190Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task VSports app下载. “…This is because lymphatic drainage in the peritoneal space is mainly directed to the gut-associated lymph nodes such as mesenteric lymph nodes [30], which are predominantly where dendritic cells present their loaded antigens to T cells and imprint gut homing signals to T reg cells for oral tolerance induction [31,32]. It has been shown that mesenteric lymph node-derived classic dendritic cells are required in peripheral T reg cell induction [33]. We anticipated that AIT for food allergies would also involve the modulation of peripheral tolerance in the mesenteric lymph nodes. …”Section: Discussionmentioningconfidence: 99%

Low-Dose Allergen-Specific Immunotherapy Induces Tolerance in a Murine Model of Shrimp Allergy

Leung1, Wai2, Shu3 et al. 2017Int Arch Allergy Immunol220210Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 4 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.