2016
DOI: 10.1111/nyas.13008
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Iron and cancer: recent insights (V体育官网入口)

Abstract: Iron is an essential dietary element. However, the ability of iron to cycle between oxidized and reduced forms also renders it capable of contributing to free radical formation, which can have deleterious effects, including promutagenic effects that can potentiate tumor formation. Dysregulation of iron metabolism can increase cancer risk and promote tumor growth. Cancer cells exhibit an enhanced dependence on iron relative to their normal counterparts, a phenomenon we have termed iron addiction. Work conducted… Show more (VSports手机版)

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Cited by 447 publications
(308 citation statements)
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