"V体育官网" NETosis Delays Diabetic Wound Healing in Mice and Humans

The Neutrophil Extracellular Traps: The Missed Link between Microvascular Inflammation and Diabetes?

Berezin1 2016Metabolomics6000Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Neutrophils that are isolated from the blood of diabetics have been shown an increased spontaneous NETosis, but an impaired inducible exaggerated NETosis response might be a leading cause of tissue damage in diabetics with healing, such as diabetic food. Moreover, NET components (elastase, histones, NGAL, and proteinase-3) were enriched in non-healing human with diabetes [19]. In was found that the finely tuned balance of NETosis required protecting the human body from microorganisms yet avoiding self-damage seems to be lost in diabetes. …”Section: Spontaneous/inducible Netosis and Diabetes-induced Vasculopathymentioningconfidence: 92%“…However, the role of spontaneous NERosis in dysmetabolic states including diabetes mellitus is not fully established. In fact, in diabetes, neutrophils are primed to release NETs and die by NETosis [19]. Neutrophils that are isolated from the blood of diabetics have been shown an increased spontaneous NETosis, but an impaired inducible exaggerated NETosis response might be a leading cause of tissue damage in diabetics with healing, such as diabetic food. …”Section: Spontaneous/inducible Netosis and Diabetes-induced Vasculopathymentioningconfidence: 99%

The Neutrophil Extracellular Traps: The Missed Link between Microvascular Inflammation and Diabetes?

Berezin1 2016Metabolomics6000Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Neutrophils that are isolated from the blood of diabetics have been shown an increased spontaneous NETosis, but an impaired inducible exaggerated NETosis response might be a leading cause of tissue damage in diabetics with healing, such as diabetic food. Moreover, NET components (elastase, histones, NGAL, and proteinase-3) were enriched in nonhealing human with diabetes (Fadini et al, 2016a). Wong SL et al (2015) have been suggested that diabetes may not only activate neutrophils to overproduce PAD4 and NETs, but NETs are as a key factor delaying wound healing. …”Section: Spontaneous / Inducible Ne-tosis In Diabetes-related Vasculomentioningconfidence: 99%

Is the neutrophil extracellular trap-driven microvascular inflammation essential for diabetes vasculopathy? (V体育官网)

Berezin1 2016Biomed Res Ther11040Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC) VSports app下载. Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…It should be assumed that the physicochemical characteristics of DNA/F-actin aggregates formed at the surface of mucosal membranes differ from that formed within tissues because assembly of negatively charged PEs is governed by local ion composition and the presence of a bundling factor (polycations), such as most cationic antibacterial peptides. Additionally the NET composition might vary based on mechanisms activating NETosis [13,18,23]. The composition of DNA-protein complexes that accumulate in airway sputum of CF patients is consistent with NETosis and joins a similar proteomic signature, indicating that the majority of the DNA in sputum is NET derived. …”Section: Dna and F-actin Accumulation In Extracellular Compartmentmentioningconfidence: 99%“…Another outcome of neutrophil accumulation leading to build-up of polyelectrolytes into the extracellular space is proteolytic action of neutrophil proteases (elastase, cathepsin G protease, and proteinase-3) that are released as both free and as a part of the NET component and are very destructive within the surrounding tissue [13,14]. In effect, DNA and F-actin gathering at infectious sites originate from neutrophils and broken host cells. …”Section: Dna and F-actin Accumulation In Extracellular Compartmentmentioningconfidence: 99%

"VSports手机版" Neutrophil extracellular traps as the main source of eDNA

Cieśluk1, Piktel2, Wątek3 et al. 2017sm6050Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 3 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.