"V体育安卓版" Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity

Transcriptome dynamics of developing maize leaves and genomewide prediction ofciselements and their cognate transcription factors

Yu1, Chen2, Chang3 et al. 2015Proc. Natl. Acad. Sci. U. S. A. 760661Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…athamap. de/) or in a collection of plant protein-binding microarray datasets (Materials and Methods and SI Appendix, Fig. S5) (68,69). If a significantly similar TFBS existed in the TF-TFBS interaction datasets, its corresponding TF was used to find the maize homologous TFs. …”Section: Expression Dynamics Of Tf Gene Families During Germination Andmentioningconfidence: 99%

Transcriptome dynamics of developing maize leaves and genomewide prediction ofciselements and their cognate transcription factors

Yu1, Chen2, Chang3 et al. 2015Proc. Natl. Acad. Sci. U. S. A VSports app下载. 760661Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Alternative methods are needed for capturing genome-wide binding data for many organisms. In vitro TFBS identification methods such as Protein Binding Microarrays (PBM) and High Throughput Systematic Evolution of Ligands by Exponential Enrichment (HT-SELEX) have achieved the highest throughput for deducing TF binding specificities in vitro [9][10][11] , but these methods use short synthetic oligonucleotides lacking secondary DNA modifications and genomic context, both important determinants of selective TF binding in vivo [12][13][14][15][16] . The DAP-seq technique 15 described here employs an in vitro-expressed affinitytagged TF in combination with high-throughput sequencing of a genomic DNA library, allowing for the generation of genome-wide binding site maps reflective of both local sequence context and DNA methylation status. …”Section: Introductionmentioningconfidence: 99%“…Successful DAPseq experiments will typically give over 5% reads in peaks and produce peaks with a significant enrichment over background. Enriched motifs such as those produced by the MEME motif discovery software can be compared to comprehensive databases of known TF binding sites 9 . Step 39-41, protein washes: ~20 min…”mentioningconfidence: 99%

Mapping genome-wide transcription-factor binding sites using DAP-seq

Bartlett1, O’Malley2, Huang3 et al. 2017Nat ProtocSelf Cite58014480Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…With RSAT, a tool specifically designed to detect regulatory signals in non‐coding sequences, we could retrieve the exact positions of experimentally determined motifs (known for most TFs but unavailable for ERF9, WRKY6, WRKY28, ZAT6, and MYB51) in the different promoters (Weirauch et al , 2014; Medina‐Rivera et al , 2015; Source Data for Appendix Fig S25). We could observe that the overall effect of the co‐regulation of two TFs depended on three factors. …”Section: Discussionmentioningconfidence: 99%“…The position‐specific scoring matrices (PSSMs) from the DNA‐binding motifs of the TFs were retrieved from the CIS‐BP database (http://cisbp. ccbr. utoronto. ca/; Weirauch et al , 2014). For five genes, ERF9 , WRKY6 , WRKY28 , ZAT6, and MYB51 , the binding motif was not yet experimentally determined and was left out of the analysis. …”Section: Methodsmentioningconfidence: 99%

From network to phenotype: the dynamic wiring of an Arabidopsis transcriptional network induced by osmotic stress

Broeck1, Dubois2, Vermeersch3 et al. 2017Molecular Systems Biology880730Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 4 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.