Direct Synthesis of High-Valent Aryl–Cu(II) and Aryl–Cu(III) Compounds: Mechanistic Insight into Arene C–H Bond Metalation (V体育ios版)

Copper-catalyzed direct acyloxylation of C(sp2)-H bonds with Benzoic acids

Zhao1, Chen2, Liu3 et al. 2015Sci. China Chem. 26060Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. “…On the basis of the experiments above and previous work on copper-catalyzed C-H functionalized [21][22][23][24][25], the reaction mechanism was tentatively proposed as shown in disproportion or oxidation to afford the C,N,N-Cu(III) species B. Finally, ligand exchange and reductive elimination from intermediate C delivered the desired product 2 with Cu(I). …”Section: Plausible Reaction Mechansimmentioningconfidence: 89%

Copper-catalyzed direct acyloxylation of C(sp2)-H bonds with Benzoic acids

Zhao1, Chen2, Liu3 et al. 2015Sci. China Chem. 26060Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task VSports app下载. “…They contain chelating ligands, for example, tris(2-pyridylthio)methyl, [17] or macrocyclic ligands [24] like N-confused porphyrins. [20] X-Ray data reveal formation of three CuAN bonds in rigid framework stabilizing Cu(II)AC bond. …”Section: Organocuprates(ii)mentioningconfidence: 99%“…Over the last years organometallic chemistry of Cu(I) and Cu(III) was vastly in progress [15,16] in contrast to Cu(II); only few stable organocuprates (II) are known to date. [17][18][19][20][21][22][23][24] Meanwhile, due to spectral data not a few labile transients, probably compounds with Cu(II)AC bond, may form in conditions of catalytic and photochemical reactions or directly by reaction of Cu(I) complexes with organic radicals. [25,26] However, the interpretation of the spectra (first of all, UV-Vis, EPR-Electron Paramagnetic Resonance) is complicated and sometimes impracticable due to the absence of analogues among corresponding well-known substances. …”Section: Introductionmentioningconfidence: 99%

Quantum chemistry of organocuprates as intermediates of catalytic and photochemical reactions

Голубева1, Gromov2, Zhidomirov3 et al. 2015Int J of Quantum Chemistry0000Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…[9][10][11] Thep ast decade has witnessed the emergence of af ew novel macrocycles. S ome aesthetic molecules such as heteracalixaromatics [12] and pillararenes [13] have been shown to be versatile synthetic receptors in host-guest chemistry. O wing to the self-tunability of electronic property and V-shaped cavity originated from the interplay between the bridging heteroatoms and adjacent aromatic rings,heteracalixaromatics are able to recognize diverse guest species. …”mentioningconfidence: 99%“…[14] Azacalix[1]arene [3]pyridines,onthe other hand, serve as awonderful model system for the elucidation of the mechanism of cupration because they form structurally well defined PhCu II and PhCu III organometallic compounds in copper(II)-catalyzed arene CÀHb ond transformations. [11] To develop macrocyclic and supramolecular chemistry,we have proposed coronarenes,anovel class of macrocycles consisting of para-(het)arylenes and heteroatoms in an alternate fashion. [15] Being different from 1,3-alternate heteracalixaromatics which form V-shaped clefts,c oronarenes contain ac ylindroid cavity. T he combination of heteroatoms and (het)arenes would advantageously generate almost limitedless diverse macrocycles of regulable cavity sizes and electronic features. W er eport herein ah ighly efficient synthesis of unprecedented water-soluble S 6 -corona [3]arene [3]pyridazines by one-pot nucleophilic aromatic substitution reaction (S N Ar) between diesters of 2,5-dimercaptoterephthalate and 3,6-dichlorotetrazine followed consecutively by the inverse electron-demand Diels-Alder reaction of tetrazine moieties with an enamine and complete hydrolysis of diester functionality. T he resulting macrocycles acted as powerful synthetic receptors to interact selectively with electron-deficient guests in water, forming 1:1complexes with an association constant up to (1. 18 AE 0. 06) 10 5 m À1 . T he first S n -corona[n]arenes (n = 4, 5), then were known as cyclic (p-phenylene sulfide)s,w ere obtained as by-products from polymerization of p-dichlorobenzene and sodium sulfide. …”mentioningconfidence: 99%

Synthesis and Molecular Recognition of Water‐Soluble S₆‐Corona[3]arene[3]pyridazines

Guo1, Zhao2, Wang3 2015Angewandte ChemieSelf Cite18030Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 4 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.