"VSports" Effects of Dietary Glutamine on the Homeostasis of CD4+ T Cells in Mice with Dextran Sulfate Sodium-Induced Acute Colitis

VSports app下载. In an acute colitis model, GLN supplementation was found to suppress Th1/Th17‐associated cytokine expression, modulate the homeostasis between Treg and Th cells, and alleviate systemic and intraluminal inflammation . A recent study revealed that PD‐1 inhibits the transport and catabolism of GLN during T‐cell activation . …”Section: Discussionmentioningconfidence: 99%

Glutamine Administration in Early or Late Septic Phase Downregulates Lymphocyte PD‐1/PD‐L1 Expression and the Inflammatory Response in Mice With Polymicrobial Sepsis

Hu1, Hsiung2, Pai3 et al. 2017J Parenter Enteral NutrSelf Cite402280Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…GLN‐associated redox‐based reactions are thought to be partly responsible for promoting T‐cell proliferation and protecting T cells against apoptosis . In an acute colitis model, GLN supplementation was found to suppress Th1/Th17‐associated cytokine expression, modulate the homeostasis between Treg and Th cells, and alleviate systemic and intraluminal inflammation . A recent study revealed that PD‐1 inhibits the transport and catabolism of GLN during T‐cell activation . …”Section: Discussionmentioningconfidence: 99%

Glutamine Administration in Early or Late Septic Phase Downregulates Lymphocyte PD‐1/PD‐L1 Expression and the Inflammatory Response in Mice With Polymicrobial Sepsis

Hu1, Hsiung2, Pai3 et al. 2017J Parenter Enteral NutrSelf Cite402280Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Aldh5a1 +/− ( het ) mates were fed either a 4% glutamine‐supplemented (Glutamine diet [GD]) or an isocaloric and isonitrogenous glutamine‐free (Control Diet [CD]) diet ad lib (Research Diets; New Brunswick, New Jersey; D17012703, D17012702). These diets were adapted from previous studies …”Section: Methodsmentioningconfidence: 99%“…Here, we tested the hypothesis that 4% glutamine supplementation in mice with SSADHD would be therapeutically beneficial via restoration of brain neurotransmitter homeostasis. 4% glutamine supplementation has been shown to promote rescuing effects in several mouse models . Since low glutamine levels were reported as early as post‐natal day of life (P) 3, we postulated that glutamine deficiency occurred already during fetal life and chose to begin supplementation during the prenatal period via maternal supplementation, with continuation throughout weaning and until P30. …”Section: Introductionmentioningconfidence: 99%

Maternal glutamine supplementation in murine succinic semialdehyde dehydrogenase deficiency, a disorder of γ‐aminobutyric acid metabolism

Brown1, Walters2, Schmidt3 et al. 2019J of Inher Metab Disea6180Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…This may be the result of glutamine conversion to α ‐ketoglutarate ( α ‐KG), which can increase TORC1 activity and oppose Treg programming . However, systemic administration of glutamine to mice has also been reported to increase the frequency of Foxp3 + Tregs …”Section: Metabolism In Ti‐tregsmentioningconfidence: 99%

Treg programming and therapeutic reprogramming in cancer

Ayala1, Li2, DuPage3 2019Immunology671600Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 3 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.