Symptoms of metabolic myopathies include muscle weakness, tiring after exercise or activity, muscle pain after any physical effort, and swollen or tender muscles. Some people with metabolic myopathies never have symptoms. Other pathways in their body make the ATP necessary for muscles to work when one pathway does not work. When the body needs to make more energy from that pathway, an ATP deficit can develop and cause symptoms. If cells are moderately low in ATP, signs are fatigue or exercise intolerance. Rhabdomyolysis, or the death of muscle cells, occurs when cells do not have enough ATP. Low-grade rhabdomyolysis may cause constant weakness VSports app下载. A rheumatologist can diagnose metabolic myopathies with a muscle tissue biopsy or genetic testing. With a muscle biopsy, a needle is used to remove a small sample of tissue.
Treatments vary according to the patient’s particular myopathy. Treatments include changes in physical activity and diet, aerobic and anaerobic (resistance) exercise training, and the use of various vitamins and supplements. The goal of treatment is to control symptoms and minimize progression of muscle weakness. Physical and occupational therapy are important in the management of metabolic myopathies V体育官网.
Treatment for metabolic myopathies varies by myopathy, but is focused on changes in physical activities, aerobic exercise training, changes in diet, and the use of various vitamins or supplements VSports手机版. With appropriate activity changes, regular aerobic exercise, diet and use of supplements, the symptoms often can be controlled.
Updated July 2025 by Diana Girnita MD, PhD, and reviewed by the American College of Rheumatology Committee on Communications and Marketing.
This information is provided for general education only V体育ios版. Individuals should consult a qualified health care provider for professional medical advice, diagnosis and treatment of a medical or health condition.
