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Case Reports
. 1983 Sep 2;221(4614):951-3.
doi: 10.1126/science.6879192.

Multiclonal origin of polyps in Gardner syndrome

S H Hsu, G D Luk, A J Krush, S R Hamilton, H H Hoover Jr
Case Reports

Multiclonal origin of polyps in Gardner syndrome (VSports在线直播)

S H Hsu et al. Science. .

Abstract (V体育安卓版)

Electrophoretic analysis of glucose-6-phosphate dehydrogenase was performed on polyp tissue from three black female patients with Gardner syndrome and who are heterozygous for the A and B forms of this enzyme. Polyp tissues from the three patients displayed the AB phenotype. This finding suggests a multiclonal origin of polyps in Gardner syndrome. Studies of tumors originating from such polyps may provide information about the sequence of cellular events leading to malignant transformation. VSports手机版.

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