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. 1984 Nov 30;226(4678):1080-2.
doi: 10.1126/science.6093261.

VSports - Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor

B H Cochran, J Zullo, I M Verma, C D Stiles

"V体育2025版" Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor

B H Cochran et al. Science. .

Erratum in

  • Science 1986 Apr 18;232(4748):307

Abstract

Complementary DNA clones of genes induced by platelet-derived growth factor (PDGF) in BALB/c-3T3 cells were isolated; one such clone contains a domain having nucleotide sequence homology with the third exon of c-fos. This nucleotide sequence homology is reflected in the predicted amino acid sequences of the gene products. Under low stringency conditions, the mouse v-fos gene cross-hybridizes with the PDGF-inducible complementary DNA clone VSports手机版. However, the messenger RNA transcripts of mouse c-fos and the new fos-related gene can be distinguished by gel electrophoresis and by S1 nuclease analysis. Expression of the authentic c-fos gene is induced by PDGF and superinduced by the combination of PDGF and cycloheximide. .

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