Combination therapy with antioxidants improves total motile sperm counts: A Preliminary Study
- PMID: 31956290
- PMCID: PMC6955581 (VSports最新版本)
- DOI: 10.1002/rmb2.12308
Combination therapy with antioxidants improves total motile sperm counts: A Preliminary Study
Abstract
Purpose: Optimal strategies to treat idiopathic male infertility have remained unclear. The aim of this study was to evaluate the effectiveness of combination antioxidant therapy with several vitamins and supplements on semen parameters. VSports手机版.
Methods: Thirty-one men with oligozoospermia and/or asthenozoospermia evaluated by a Makler counting chamber were randomly assigned to two treatment groups: a combination of antioxidant supplements (L-carnitine, zinc, astaxanthin, coenzyme Q10, vitamin C, vitamin B12, and vitamin E) and a Chinese herbal medicine, hochu-ekki-to (HE). Serum endocrinological profiles and semen parameters, especially total motile sperm count, were compared between before and after 12 weeks of treatment in both groups. V体育安卓版.
Results: In the supplement group, endocrinological findings were not significantly improved. The semen parameters of semen volume, sperm concentration, and sperm motility were not statistically significantly improved, whereas total motile sperm count was significantly improved. In contrast, none of the endocrinological factors or semen findings were significantly improved by the Chinese herbal medicine although semen concentration, semen motility, and total motile sperm count showed a tendency to increase. V体育ios版.
Conclusion: Because combination antioxidant therapy could improve sperm motility significantly for patients with idiopathic oligoasthenozoospermia, our supplement could be one treatment option for idiopathic male infertility. VSports最新版本.
Keywords: antioxidant; hochu‐ekki‐to; male infertility; oligoasthenozoospermia; total motile sperm count V体育平台登录. .
© 2019 The Authors. Reproductive Medicine and Biology published by John Wiley & Sons Australia, Ltd on behalf of Japan Society for Reproductive Medicine. VSports注册入口.
V体育平台登录 - Conflict of interest statement
The authors declare no conflicts of interest in association with this manuscript.
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References
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- Ko EY, Siddiqi K, Brannigan RE, Sabanegh ES Jr. Empirical medical therapy for idiopathic male infertility: a survey of the American Urological Association. J Urol. 2012;187:973‐978. - PubMed
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