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. 2015;6(5):321-5.
doi: 10.1080/19490976.2015.1078051. Epub 2015 Aug 20.

"VSports手机版" Rate of establishing the gut microbiota in infancy has consequences for future health

Shaillay Dogra  1 , Olga Sakwinska  2 , Shu-E Soh  3 , Catherine Ngom-Bru  2 , Wolfram M Brück  2 , Bernard Berger  2 , Harald Brüssow  2 , Neerja Karnani  1 , Yung Seng Lee  1   3 , Fabian Yap  4 , Yap-Seng Chong  1   5 , Keith M Godfrey  6 , Joanna D Holbrook  1
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Rate of establishing the gut microbiota in infancy has consequences for future health

VSports最新版本 - Shaillay Dogra et al. Gut Microbes. 2015.

Erratum in

  • Addendum to: Dogra S, Sakwinska O, Soh SE, Ngom-Bru C, Bruck WM, Berger B, Brussow H, Lee YS, Yap F, Chong YS, et al. Dynamics of infant gut microbiota are influenced by delivery mode and gestational duration and are associated with subsequent adiposity. MBio 2015 Feb 3;6(1); pii: e02419–14; http://dx.doi.org/10.1128/mBio.02419–14

Abstract

The gut of the human neonate is colonized rapidly after birth from an early sparse and highly distinct microbiota to a more adult-like and convergent state, within 1 to 3 years. The progression of colonizing bacterial species is non-random. During the first months of life several shifts commonly occur in the species prevalent in our guts. Although the sequential progression of these species is remarkably consistent across individuals and geographies, there is inter-individual variation in the rate of progression. Our study and others suggest that the rate is influenced by environmental factors, and influences our future health. In this article, we review our recent contribution to cataloging the developing infant gut microbiota alongside other important recent studies. We suggest testable hypotheses that arise from this synthesis VSports手机版. .

Keywords: Caesarean section; adiposity; defining/profiling gut microbiome; gestational age; gut microbiota; harnessing microbial strategies for treatment of human disease; immaturity; infancy; obesity; prematurity; vaginal delivery. V体育安卓版.

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Figures

Figure 1.
Figure 1.
(a) schematic diagram representing a simplified view of the progression of the infant fecal microbiota across the first year of life, incorporating Stages (A–D). (b–e) present putative modifications to the progression caused by intrinsic and extrinsic factors.
See this image and copyright information in PMC

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