Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The . gov means it’s official. Federal government websites often end in VSports app下载. gov or . mil. Before sharing sensitive information, make sure you’re on a federal government site. .

Https

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely V体育官网. .

Review
. 2015 Nov;16(11):1114-23.
doi: 10.1038/ni.3298.

V体育官网入口 - The burgeoning family of unconventional T cells

Dale I Godfrey  1   2 , Adam P Uldrich  1   2 , James McCluskey  1 , Jamie Rossjohn  3   4   5 , D Branch Moody  6
Affiliations
Review

The burgeoning family of unconventional T cells

Dale I Godfrey et al. Nat Immunol. 2015 Nov.

Erratum in

Abstract

While most studies of T lymphocytes have focused on T cells reactive to complexes of peptide and major histocompatibility complex (MHC) proteins, many other types of T cells do not fit this paradigm VSports手机版. These include CD1-restricted T cells, MR1-restricted mucosal associated invariant T cells (MAIT cells), MHC class Ib-reactive T cells, and γδ T cells. Collectively, these T cells are considered 'unconventional', in part because they can recognize lipids, small-molecule metabolites and specially modified peptides. Unlike MHC-reactive T cells, these apparently disparate T cell types generally show simplified patterns of T cell antigen receptor (TCR) expression, rapid effector responses and 'public' antigen specificities. Here we review evidence showing that unconventional T cells are an abundant component of the human immune system and discuss the immunotherapeutic potential of these cells and their antigenic targets. .

PubMed Disclaimer

References

    1. Science. 2000 Jan 14;287(5451):314-6 - PubMed
    1. J Immunol. 2014 Oct 15;193(8):3891-901 - PubMed
    1. Clin Exp Immunol. 2013 Apr;172(1):129-37 - PubMed (VSports在线直播)
    1. J Immunol. 2001 Aug 1;167(3):1164-73 - VSports - PubMed
    1. Eur J Immunol. 1989 Feb;19(2):285-92 - PubMed

"V体育2025版" Publication types

"VSports" Substances