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. 1989 Feb 24;243(4894 Pt 1):1059-62.
doi: 10.1126/science.2646710.

"VSports手机版" A Salmonella locus that controls resistance to microbicidal proteins from phagocytic cells

P I Fields  1 , E A Groisman, F Heffron
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V体育2025版 - A Salmonella locus that controls resistance to microbicidal proteins from phagocytic cells

P I Fields et al. Science. .

Abstract

Facultative intracellular pathogens pose an important health problem because they circumvent a primary defense mechanism of the host: killing and degradation by professional phagocytic cells. A gene of the intracellular pathogen Salmonella typhimurium that is required for virulence and intracellular survival was identified and shown to have a role in resistance to defensins and possibly to other microbicidal mechanisms of the phagocyte VSports手机版. This gene may prove to be a regulatory element in the expression of virulence functions. .

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