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Comparative Study
. 1989;6(3):349-53.
doi: 10.1007/BF01047853.

"V体育安卓版" Conserved sequences in bacterial and viral sialidases

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Comparative Study

Conserved sequences in bacterial and viral sialidases

VSports - P Roggentin et al. Glycoconj J. 1989.

Abstract

The genes of the bacterial sialidases from Clostridium sordellii G12, C. perfringens A99, Salmonella typhimurium LT-2 and Vibrio cholerae 395 sequenced so far were examined for homologies and were compared with sequences of viral sialidases. Each of the bacterial sialidases contains a short sequence of twelve amino-acids, which is repeated at four positions in the protein. All these sequences exhibit significant similarities. Comparing the repeated sequences of the four sialidases, five amino-acids were found to be highly conserved at defined positions: Ser-X-Asp-X-Gly-X-Thr-Trp VSports手机版. Additionally, most of the distances between the four repeated regions are also conserved among the different sialidases. The conserved bacterial sequences show similarity with sialidases of influenza A H7N1 and H13N9. .

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"V体育官网" References

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    1. Proc Natl Acad Sci U S A. 1982 Nov;79(22):6817-21 - PubMed
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