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Case Reports
. 2014 Sep;18(Suppl 1):S139-42.
doi: 10.4103/0973-029X.141369.

V体育官网入口 - Oral Crohn's disease

Bn Padmavathi  1 , Smriti Sharma  1 , Madhusudan Astekar  2 , Y Rajan  1 , Gv Sowmya  3
Affiliations
Case Reports

Oral Crohn's disease

Bn Padmavathi et al. J Oral Maxillofac Pathol. 2014 Sep.

VSports app下载 - Abstract

'Crohn's disease' is an inflammatory granulomatous disease of the gastrointestinal tract with extra-intestinal manifestations. Oral lesions may precede the intestinal disease and serve as a source for histological diagnosis. We present a case of orofacial Crohn's disease where orofacial symptoms were present for about 13 years and occasional constipation was present, since 6 months. Oral examination plays an important role in early diagnosis of Crohn's disease. VSports手机版.

Keywords: Crohn's disease; chronic; cobblestone; colitis; granuloma; granulomatous disease; granulomatous enteritis; oral; pediatric crohn. V体育安卓版.

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Conflict of interest statement (VSports app下载)

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
The clinical photograph showing diffuse enlargement of face and lips
Figure 2
Figure 2
The intraoral photograph showing bead like gingival enlargement
Figure 3
Figure 3
The intraoral photograph showing cobble stone appearance with hyperplastic mucosal folds on left side of buccal mucosa
Figure 4
Figure 4
The intraoral photograph showing hyperplasia of palatal mucosa
Figure 5
Figure 5
Photomicrograph showing a parakeratinized stratified squamous epithelium along with the underlying granuloma formation. (a – H&E stain, ×40. b and c – H&E stain, ×100). Photomicrograph shows scattered aggregates of non-caseating granuloma (d and e – H&E stain, ×200) which are typically small consisting of macrophages, epitheloid cells surrounded by scattered lymphocytes and plasma cells (f – H&E stain, ×400)
Figure 6
Figure 6
The Colonoscopy showing clinical inflammation of colon
See this image and copyright information in PMC

References

    1. Pittock S, Drumm B, Fleming P, McDermott M, Imrie C, Flint S, et al. The oral cavity in Crohn's disease. J Pediatr. 2001;138:767–71. - PubMed
    1. Naser SA, Arce M, Khaja A, Fernandez M, Naser N, Elwasila S, et al. Role of ATG16L, NOD2 and IL23R in Crohn's disease pathogenesis. World J Gastroenterol. 2012;18:412–24. - PMC - PubMed
    1. Michailidou E, Arvanitidou S, Lombardi T, Kolokotronis A, Antoniades D, Samson J, et al. Oral lesions leading to the diagnosis of Crohn disease: Report on 5 patients. Quintessence Int. 2009;40:581–8. - PubMed
    1. Rowland M, Fleming P, Bourke B. Looking in the mouth for Crohn's disease. Inflamm Bowel Dis. 2010;16:332–7. - PubMed
    1. Galbraith SS, Drolet BA, Kugathasan S, Paller AS, Esterly NB. Asymptomatic inflammatory bowel disease presenting with mucocutaneous findings. Pediatrics. 2005;116:e439–44. - PubMed

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