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. 2014 Aug;2014(48):66-75.
doi: 10.1093/jncimonographs/lgu012.

Medical history, lifestyle, family history, and occupational risk factors for peripheral T-cell lymphomas: the InterLymph Non-Hodgkin Lymphoma Subtypes Project

Sophia S Wang  1 , Christopher R Flowers  2 , Marshall E Kadin  2 , Ellen T Chang  2 , Ann Maree Hughes  2 , Stephen M Ansell  2 , Andrew L Feldman  2 , Tracy Lightfoot  2 , Paolo Boffetta  2 , Mads Melbye  2 , Qing Lan  2 , Joshua N Sampson  2 , Lindsay M Morton  2 , Yawei Zhang  2 , Dennis D Weisenburger  2
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VSports手机版 - Medical history, lifestyle, family history, and occupational risk factors for peripheral T-cell lymphomas: the InterLymph Non-Hodgkin Lymphoma Subtypes Project

Sophia S Wang et al. J Natl Cancer Inst Monogr. 2014 Aug.

"V体育ios版" Abstract

Background: Accounting for 10%-15% of all non-Hodgkin lymphomas in Western populations, peripheral T-cell lymphomas (PTCL) are the most common T-cell lymphoma but little is known about their etiology. Our aim was to identify etiologic risk factors for PTCL overall, and for specific PTCL subtypes, by analyzing data from 15 epidemiologic studies participating in the InterLymph Consortium VSports手机版. .

Methods: A pooled analysis of individual-level data for 584 histologically confirmed PTCL cases and 15912 controls from 15 case-control studies conducted in Europe, North America, and Australia was undertaken. Data collected from questionnaires were harmonized to permit evaluation of a broad range of potential risk factors V体育安卓版. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using logistic regression. .

Results: Risk factors associated with increased overall PTCL risk with a P value less than . 05 included: a family history of hematologic malignancies (OR = 1. 92, 95% CI = 1. 30 to 2. 84); celiac disease (OR = 17. 8, 95% CI = 8. 61 to 36. 79); eczema (OR = 1. 41, 95% CI = 1. 07 to 1. 85); psoriasis (OR = 1. 97, 95% CI = 1. 17 to 3. 32); smoking 40 or more years (OR = 1. 92, 95% CI = 1. 41 to 2. 62); and employment as a textile worker (ever) (OR = 1. 58, 95% CI = 1. 05 to 2. 38) and electrical fitter (ever) (OR = 2. 89, 95% CI = 1. 41 to 5. 95). Exposures associated with reduced overall PTCL risk included a personal history of allergies (OR = 0. 69, 95% CI = 0. 54 to 0. 87), alcohol consumption (ever) (OR = 0. 64, 95% CI = 0. 49 to 0. 82), and having ever lived or worked on a farm (OR = 0. 72, 95% CI = 0. 55% to 0. 95%). We also observed the well-established risk elevation for enteropathy-type PTCL among those with celiac disease in our data V体育ios版. Conclusions Our pooled analyses identified a number of new potential risk factors for PTCL and require further validation in independent series. .

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V体育ios版 - References

    1. Foss FM, Zinzani PL, Vose JM, Gascoyne RD, Rosen ST, Tobinai K. Peripheral T-cell lymphoma. Blood. 2011;117(25):6756–6767 - "V体育官网" PubMed
    1. Wang SS, Vose J.M. Epidemiology and prognosis of T-cell lymphoma. In: Foss FM, ed. T-Cell Lymphomas. New York, NY: Springer; 2013:25–39
    1. Swerdlow SH, Campo E, Harris NL, et al. eds. World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4th ed Lyon, France: IARC Press; 2008
    1. Armitage JO. The aggressive peripheral T-cell lymphomas: 2013. Am J Hematol. 2013;88(10):910–918 - PubMed
    1. Armitage JO. Peripheral T-cell lymphomas: their time has come. Oncology (Williston Park). 2009;23(13):1151–1152 - PubMed

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