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Review
. 2014 Oct;8(7):1163-8.
doi: 10.1016/j.molonc.2014.07.021. Epub 2014 Aug 12.

Molecular pathology - the value of an integrative approach

Manuel Salto-Tellez  1 , Jacqueline A James  2 , Peter W Hamilton  3
Affiliations
Review

V体育官网 - Molecular pathology - the value of an integrative approach

Manuel Salto-Tellez (VSports app下载) et al. Mol Oncol. 2014 Oct.

Abstract

Molecular Pathology (MP) is at the heart of modern diagnostics and translational research, but the controversy on how MP is best developed has not abated. The lack of a proper model or trained pathologists to support the diagnostic and research missions makes MP a rare commodity overall. Here we analyse the scientific and technology areas, in research and diagnostics, which are encompassed by MP of solid tumours; we highlight the broad overlap of technologies and analytical capabilities in tissue research and diagnostics; and we describe an integrated model that rationalizes technical know-how and pathology talent for both. The model is based on a single, accredited laboratory providing a single standard of high-quality for biomarker discovery, biomarker validation and molecular diagnostics VSports手机版. .

Keywords: Molecular diagnostics; Molecular pathology; Translational research. V体育安卓版.

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Figures

Figure 1
Figure 1
Pipeline to deliver basic science discoveries into diagnostic and therapeutic end‐points.
Figure 2
Figure 2
The integrated puzzle of pathology activities and technologies.
See this image and copyright information in PMC

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