Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The . gov means it’s official. Federal government websites often end in . gov or VSports app下载. mil. Before sharing sensitive information, make sure you’re on a federal government site. .

Https

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. V体育官网.

Review
. 2012 Jul 11;13(8):499-507.
doi: 10.1038/nrm3391.

VSports app下载 - H₂S signalling through protein sulfhydration and beyond

Bindu D Paul  1 , Solomon H Snyder
Affiliations
Review

V体育ios版 - H₂S signalling through protein sulfhydration and beyond

Bindu D Paul et al. Nat Rev Mol Cell Biol. .

Abstract

Hydrogen sulfide (H(2)S) has recently emerged as a mammalian gaseous messenger molecule, akin to nitric oxide and carbon monoxide. H(2)S is predominantly formed from Cys or its derivatives by the enzymes cystathionine β-synthase and cystathionine γ-lyase. One of the mechanisms by which H(2)S signals is by sulfhydration of reactive Cys residues in target proteins. Although analogous to protein nitrosylation, sulfhydration is substantially more prevalent and usually increases the catalytic activity of targeted proteins VSports手机版. Physiological actions of sulfhydration include the regulation of inflammation and endoplasmic reticulum stress signalling as well as of vascular tension. .

PubMed Disclaimer

Comment in

  • The conversion of H(2)S to sulfane sulfur.
    Toohey JI. Toohey JI. Nat Rev Mol Cell Biol. 2012 Dec;13(12):803; author reply p.803. doi: 10.1038/nrm3391-c1. Epub 2012 Nov 15. Nat Rev Mol Cell Biol. 2012. PMID: 23151660 No abstract available.

V体育官网 - References

    1. Curr Opin Chem Biol. 2008 Feb;12(1):18-24 - PubMed
    1. Nat Cell Biol. 2001 Feb;3(2):193-7 - "V体育官网" PubMed
    1. Hepatology. 2009 Jan;49(1):141-50 - VSports手机版 - PubMed
    1. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1293-8 - V体育平台登录 - PubMed
    1. Pflugers Arch. 2010 May;459(6):863-79 - PubMed

MeSH terms

V体育官网 - Grants and funding

LinkOut - more resources