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Review
. 2012 Feb 14:5:3.
doi: 10.1186/1756-8722-5-3.

Current management and novel agents for malignant melanoma

Byung Lee  1 , Nikhil Mukhi, Delong Liu
Affiliations
Review

Current management and novel agents for malignant melanoma

Byung Lee et al. J Hematol Oncol. .

Abstract

Advanced malignant melanoma remains a challenging cancer VSports手机版. Over the past year, there have been 3 agents approved for treatment of melanoma by Food and Drug Administration. These include pegylated interferon alpha-2b for stage III melanoma, vemurafenib for unresectable or metastatic melanoma with BRAF V600E mutation, and ipilimumab for treatment of unresectable or metastatic melanoma. This review will also update on the development of novel agents, including tyrosine kinase inhibitors and adoptive cellular therapy. .

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Figures

Figure 1
Figure 1
The mechanism of action of anti-CTLA-4 monoclonal antibody.
Figure 2
Figure 2
Molecular structure of B-RAF and the V600E (valine to glutamic acid) missense mutation. C: carboxyl-terminal; N: amino-terminal.
See this image and copyright information in PMC

"VSports" References

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VSports在线直播 - MeSH terms

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