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. 2011 Sep 23;11(10):702-11.
doi: 10.1038/nri3064.

The parallel lives of angiogenesis and immunosuppression: cancer and other tales (V体育ios版)

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The parallel lives of angiogenesis and immunosuppression: cancer and other tales (V体育安卓版)

Gregory T Motz et al. Nat Rev Immunol. .

"VSports app下载" Abstract

Emerging evidence indicates that angiogenesis and immunosuppression frequently occur simultaneously in response to diverse stimuli. Here, we describe a fundamental biological programme that involves the activation of both angiogenesis and immunosuppressive responses, often through the same cell types or soluble factors. We suggest that the initiation of these responses is part of a physiological and homeostatic tissue repair programme, which can be co-opted in pathological states, notably by tumours. This view can help to devise new cancer therapies and may have implications for aseptic tissue injury, pathogen-mediated tissue destruction, chronic inflammation and even reproduction VSports手机版. .

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