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. 2011 Oct;65(4):227-30.
doi: 10.1111/j.1600-0536.2011.01907.x. Epub 2011 Jul 1.

"VSports" Lack of effect of ustekinumab in treatment of allergic contact dermatitis

Nannie Bangsgaard  1 , Claus Zachariae, Torkil Menné, Lone Skov
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VSports最新版本 - Lack of effect of ustekinumab in treatment of allergic contact dermatitis

Nannie Bangsgaard et al. Contact Dermatitis. 2011 Oct.

Abstract (V体育安卓版)

Background: Allergic contact dermatitis is a chronic inflammatory T cell mediated disease that can be recalcitrant to existing treatments. Ustekinumab is a monocloncal antibody blocking IL-12 and IL-23, shown to be effective and safe for patients with psoriasis. Despite both IL-12 and IL-23 involvement in contact allergy, the effect of Ustekinumab on allergic contact dermatitis has not been reported. VSports手机版.

Objectives: To evaluate the clinical effect of Ustekinumab in patients with allergic contact dermatitis. V体育安卓版.

Methods: A retrospective, case cohort study of patients with allergic contact dermatitis treated with Ustekinumab in our department. V体育ios版.

Results: Five patients had been treated with Ustekinumab for allergic contact dermatitis, with limited effect. VSports最新版本.

Conclusion: Our observation suggests that, although theoretically plausible, Ustekinumab does not seem to be a valuable therapeutic approach for chronic allergic contact dermatitis. V体育平台登录.

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