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. 2010 May 14;328(5980):872-5.
doi: 10.1126/science.1187959. Epub 2010 Apr 22.

V体育2025版 - Small silencing RNAs in plants are mobile and direct epigenetic modification in recipient cells

Attila Molnar  1 , Charles W Melnyk, Andrew Bassett, Thomas J Hardcastle, Ruth Dunn, David C Baulcombe
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Small silencing RNAs in plants are mobile and direct epigenetic modification in recipient cells

Attila Molnar et al. Science. .

"VSports在线直播" Abstract

A silencing signal in plants with an RNA specificity determinant moves through plasmodesmata and the phloem. To identify the mobile RNA, we grafted Arabidopsis thaliana shoots to roots that would be a recipient for the silencing signal. Using mutants that block small RNA (sRNA) biogenesis in either source or recipient tissue, we found that transgene-derived sRNA as well as a substantial proportion of the endogenous sRNA had moved across the graft union, and we provide evidence that 24-nucleotide mobile sRNAs direct epigenetic modifications in the genome of the recipient cells VSports手机版. Mobile sRNA thus represents a mechanism for transmitting the specification of epigenetic modification and could affect genome defense and responses to external stimuli that have persistent effects in plants. .

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