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Review
. 2010 Feb;10(2):123-30.
doi: 10.1038/nri2690.

Intracellular DNA recognition

Veit Hornung  1 , Eicke Latz
Affiliations
Review

Intracellular DNA recognition

Veit Hornung et al. Nat Rev Immunol. 2010 Feb.

V体育ios版 - Abstract

The recognition of nucleic acids is one strategy by which cells can detect infectious agents. As life is ultimately determined by the existence of nucleic acids, this defence strategy has evolved in many different organisms and operates effectively in many different cell types. Here, we review the recent progress in our understanding of the molecular mechanisms by which DNA activates cells to induce inflammation and antimicrobial immunity. DNA can be detected in different cellular compartments and can induce a range of cellular responses, such as an antiviral response and pyroptotic cell death together with the maturation and release of active interleukin-1beta. VSports手机版.

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References

    1. Immunity. 2006 Jan;24(1):93-103 - PubMed
    1. Nature. 2007 Jul 26;448(7152):501-5 - PubMed
    1. Nat Genet. 2001 Aug;28(4):313-4 - "V体育安卓版" PubMed
    1. Nat Genet. 2006 Aug;38(8):917-20 - "V体育2025版" PubMed
    1. Immunity. 2009 Mar 20;30(3):397-407 - PubMed

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