Splice junctions follow a 205-base ladder
- PMID: 2006175
- PMCID: PMC51235
- DOI: 10.1073/pnas.88.6.2380
"VSports" Splice junctions follow a 205-base ladder
VSports在线直播 - Abstract
Of all aspects of mRNA maturation the accuracy of intervening sequence excision and exon ligation is, perhaps, the most enigmatic. Attempts to identify the essential elements involved in this process have thus far not yielded any satisfactory answer as to what structural (sequence) features are prerequisite for the vital precision of this process. In our search for underlying structural orders we asked whether exons and introns had any positional preferences within a gene VSports手机版. This analysis led to the unexpected discovery that the DNA length is synchronized between successive 3' splicing sites as well as between successive 5' splicing sites, with a frame of approximately 205 base pairs. This observation reveals additional organization of genes in eukaryotes and, perhaps, links gene splicing with chromatin structure. .
References
-
- Nucleic Acids Res. 1980 Jan 11;8(1):21-42 - PubMed
-
- Annu Rev Biochem. 1980;49:421-57 - "V体育官网" PubMed
-
- Mol Biol Rep. 1981 May 22;7(1-3):149-58 - "VSports" PubMed
-
- Nature. 1989 Nov 16;342(6247):243-7 - PubMed (VSports在线直播)
-
- Nucleic Acids Res. 1988 Nov 11;16(21):9893-908 - VSports - PubMed
MeSH terms
- Actions (V体育ios版)
- VSports在线直播 - Actions
- Actions (VSports app下载)
VSports手机版 - Substances
LinkOut - more resources
Full Text Sources
