Background: We sought to define current incidence trends and outcomes for children with lung and bronchus tumors. VSports手机版.

Methods: The SEER registry was queried from 1973 to 2004 for all patients with pulmonary tumors less than 20 y of age V体育安卓版. .

Results: Overall, 160 patients were identified. The age-adjusted incidence has remained stable at 0. 049 per 100,000 persons. The median age at diagnosis was 16 y. Whites had the highest age-adjusted population incidence at 0. 056 per 100,000. Most tumors arose in the lower lobe (37%), followed by the upper lobe (31. 2%). The most common histology was endocrine tumor (51. 6%), followed by sarcoma (11%), and mucoepidermoid tumor (9%). Overall survival was greater than 381 mo with a 15-y survival of 65%. Males had better survival (>381 versus 288 months). Endocrine and mucoepidermoid tumors had the best survival. Small cell carcinoma had the worst median survival at less than 5 mo. Squamous cell carcinoma and adenocarcinoma both had a 14-mo median survival. Median survival for nonsurgically treated patients was 14 mo with a 10-y survival rate of 32%. Surgery improved the 10-y survival to 75% (P<0. 0001). Multivariate analysis demonstrated nonsurgical treatment and nonendocrine tumor histology to be independent prognostic factors of death. V体育ios版.

Conclusion: The incidence of pediatric lung cancer remains stable. Several factors, including nonsurgical treatment and nonendocrine tumors confer a poor prognosis. Early diagnosis and surgical therapy provide the best chance for survival VSports最新版本. .