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Review
. 2009 Jul;40(7):909-17.
doi: 10.1016/j.humpath.2009.04.001.

Pathology of graft-versus-host disease in the gastrointestinal tract

Kay Washington  1 , Madan Jagasia
Affiliations
Review

Pathology of graft-versus-host disease in the gastrointestinal tract

Kay Washington et al. Hum Pathol. 2009 Jul.

Abstract

Graft-versus-host disease (GVHD), a common complication of hematopoietic stem cell transplantation, is a clinical syndrome that requires synthesis of clinical, laboratory, and histopathologic findings for diagnosis. The gastrointestinal (GI) tract is commonly affected, and pathologists must recognize subtle morphologic alterations in GI mucosal biopsies to make the diagnosis and to rule out other causes of GI dysfunction such as cytomegalovirus infection and drug effects. This review summarizes the histopathologic features of GVHD in the GI tract and outlines recent recommendations for reporting of GI biopsies with suspected GVHD VSports手机版. .

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