Background: The World Health Organization developed a time to pregnancy (TTP) study (number of menstrual cycles taken to conceive) to determine whether the average TTP is increasing and semen quality decreasing with time. The present study describes clinical, semen and hormone characteristics obtained from male partners of pregnant women in Melbourne, Australia, and examines the associations between these characteristics. VSports手机版.

Methods: Male partners (n = 225) of pregnant women (16-32 weeks) who conceived naturally had physical examination, health and lifestyle questionnaires, semen and hormone (FSH, LH, sex hormone-binding globulin, testosterone and Inhibin B) analyses V体育安卓版. .

Results: Previously known associations between semen, hormone and clinical variables were confirmed as significant: sperm numbers (concentration and total sperm count) correlated positively with Inhibin B and inversely with FSH and left varicocele, while total testicular volume correlated positively with sperm numbers and Inhibin B and inversely with FSH. However, only abstinence, total testicular volume, varicocele grade and obesity (BMI > 30 kg/m2) were independently significantly related to total sperm count V体育ios版. Compared with those with BMI < 30 (n = 188), obese subjects (n = 35) had significantly lower total sperm count (mean 324 versus 231 million, P = 0. 013) and Inhibin B (187 versus 140 pg/ml, P < 0. 001) but not FSH (3. 4 versus 4. 0 IU/l, P = 0. 6). .

Conclusions: Obese fertile men appear to have reduced testicular function VSports最新版本. Whether this is cause or effect, i. e. adiposity impairing spermatogenesis or reduced testicular function promoting fat deposition, remains to be determined. .