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Review
. 2009 May;9(5):361-71.
doi: 10.1038/nrc2628. Epub 2009 Apr 3.

VSports手机版 - Tumour necrosis factor and cancer

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Review

"V体育官网" Tumour necrosis factor and cancer

Frances Balkwill (V体育平台登录). Nat Rev Cancer. 2009 May.

Abstract

Tumour necrosis factor (TNF) is a major inflammatory cytokine that was first identified for its ability to induce rapid haemorrhagic necrosis of experimental cancers. When efforts to harness this anti-tumour activity in cancer treatments were underway, a paradoxical tumour-promoting role of TNF became apparent. Now that links between inflammation and cancer are appreciated, is TNF a target or a therapeutic in malignant disease -- or both VSports手机版. .

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References

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    1. Clin Cancer Res. 2004 Oct 1;10(19):6528-34 - PubMed
    1. Proc Natl Acad Sci U S A. 1989 Jul;86(13):5064-8 - V体育平台登录 - PubMed
    1. Cancer Res. 2007 Feb 1;67(3):1038-45 - PubMed
    1. Nature. 1984 Dec 20-1985 Jan 2;312(5996):721-4 - PubMed

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V体育平台登录 - Grants and funding

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