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Review
. 2008 Jun 12;3(6):344-7.
doi: 10.1016/j.chom.2008.05.010.

Commensals, bacterial pathogens and intestinal inflammation: an intriguing ménage à trois

Thierry Pédron  1 , Philippe Sansonetti
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Free article
Review

"V体育2025版" Commensals, bacterial pathogens and intestinal inflammation: an intriguing ménage à trois

Thierry Pédron et al. Cell Host Microbe. .
Free article

Abstract

According to a classical view of bacterial-host interactions at intestinal surfaces, the commensal microbiota establishes tolerance, and invasive pathogens cause stereotypic inflammation VSports手机版. The reality is more complex, marked by a "ménage à trois" situation encompassing three emerging concepts: (1) pathogens take advantage of inflammation to cross the epithelial barrier, (2) pathogens reduce the commensal flora to invade their niche, and (3) pathogens express dedicated effectors that modulate inflammation. .

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