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Multicenter Study
. 2007 Apr;55(4):518-25.
doi: 10.1111/j.1532-5415.2007.01100.x.

Influence of comorbid conditions on long-term mortality after pneumonia in older people

Affiliations
Multicenter Study

Influence of comorbid conditions on long-term mortality after pneumonia in older people

Sachin Yende et al. J Am Geriatr Soc. 2007 Apr.

Abstract (V体育ios版)

Objectives: To test the hypothesis that increased long-term mortality after hospitalization for community-acquired pneumonia (CAP) is independent of comorbid conditions. VSports手机版.

Design: Prospective observational cohort study in metropolitan areas V体育安卓版. .

Setting: Memphis, Tennessee, and Pittsburgh, Pennsylvania. V体育ios版.

Participants: Three thousand seventy-five subjects aged 70 to 79 over 5. 2 years VSports最新版本. .

Measurements: Unadjusted and adjusted mortality from an initial hospitalization for CAP were compared with mortality from different causes of hospitalization, including cancer, fracture, congestive heart failure (CHF), cerebrovascular accident (CVA), and other causes. Demographics, smoking, nutritional markers, functional status, inflammatory markers, and chronic health conditions were adjusted for V体育平台登录. .

Results: Of the 106 subjects hospitalized for CAP, 22 (20 VSports注册入口. 8%) and 38 (35. 8%) died at 1 and 5 years. Subjects hospitalized with CAP had higher mortality than nonhospitalized subjects (adjusted odds ratio (OR)=7. 8, 95% confidence interval (CI)=4. 2-14. 4). One- and 5-year mortality after CAP hospitalization were higher than mortality from other causes requiring hospitalization and remained unchanged in multivariable analysis (adjusted OR=3. 5, 95% CI=1. 5-8. 1; adjusted OR=5. 6, 95% CI=2. 8-11. 2, respectively). One- and 5-year mortality after hospitalization for CAP were similar to or higher than mortality after an initial hospitalization for CHF, CVA, or fracture. Rehospitalization was common in subjects hospitalized for CAP and may explain greater long-term mortality. .

Conclusion: In this high-functioning cohort of older persons, an initial hospitalization for CAP was associated with greater long-term mortality, independent of prehospitalization comorbid conditions. Hospitalization for CAP has as serious a prognosis as hospitalization for CHF, stroke, or major fracture. V体育官网入口.

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