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Review
. 2006 Apr;11(2):151-63.
doi: 10.1007/s10911-006-9021-5.

Probing the microenvironment of mammary tumors using multiphoton microscopy

Mazen Sidani  1 , Jeffrey Wyckoff, Chengsen Xue, Jeffrey E Segall, John Condeelis
Affiliations
Review

Probing the microenvironment of mammary tumors using multiphoton microscopy

Mazen Sidani et al. J Mammary Gland Biol Neoplasia. 2006 Apr.

"V体育安卓版" Abstract

Advances in optical imaging technologies that allow the subcellular resolution of undissected tissue have begun to offer new clues into the biology of development and disease. For cancer, such advances mean that the primary tumor is no longer a black box and that the disease can be studied throughout the metastatic cascade and not just as an endpoint. In this review we examine the advances in multiphoton imaging technology that have been used to define the microenvironment and its role in delineating the invasion and intravasation steps of metastasis inside living mammary tumors. Results show that the tumor microenvironment is a dynamic place where interactions between tumor cells, macrophages, blood vessels, and extracellular matrix fibers define the metastatic phenotype VSports手机版. .

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References

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