VSports - Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The . gov means it’s official. Federal government websites often end in . gov or . mil VSports app下载. Before sharing sensitive information, make sure you’re on a federal government site. .

Https

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. V体育官网.

Review
. 2006 Feb 24;124(4):783-801.
doi: 10.1016/j.cell.2006.02.015.

Pathogen recognition and innate immunity

Shizuo Akira  1 , Satoshi Uematsu, Osamu Takeuchi
Affiliations
Free article
Review

Pathogen recognition and innate immunity

Shizuo Akira et al. Cell. .
Free article

Abstract (V体育安卓版)

Microorganisms that invade a vertebrate host are initially recognized by the innate immune system through germline-encoded pattern-recognition receptors (PRRs) VSports手机版. Several classes of PRRs, including Toll-like receptors and cytoplasmic receptors, recognize distinct microbial components and directly activate immune cells. Exposure of immune cells to the ligands of these receptors activates intracellular signaling cascades that rapidly induce the expression of a variety of overlapping and unique genes involved in the inflammatory and immune responses. New insights into innate immunity are changing the way we think about pathogenesis and the treatment of infectious diseases, allergy, and autoimmunity. .

PubMed Disclaimer

"VSports" Publication types

MeSH terms (VSports)

LinkOut - more resources